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Iranian Journal of Otorhinolaryngology، جلد ۲۷، شماره ۴، صفحات ۲۸۵-۲۹۱
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| عنوان انگلیسی |
Intra-Operative Lymphatic Mapping and Sentinel Node Biopsy in Laryngeal Carcinoma: Preliminary Results |
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| چکیده انگلیسی مقاله |
Introduction: Sentinel node mapping has been used for laryngeal carcinoma in several studies, with excellent results thus far.In the current study, we report our preliminary results on sentinel node mapping in laryngeal carcinoma using intra-operative peri-tumoral injection of a radiotracer. Materials and Methods: Patients with biopsy-proven squamous cell carcinoma of the larynx were included in the study. Two mCi/0.4 cc Tc-99m-phytate in four aliquots was injected on the day of surgery, after induction of anesthesia, in the sub-mucosal peri-tumoral location using a suspension laryngoscopy. After waiting for 10 minutes, a portable gamma probe was used to search for sentinel nodes. All patients underwent laryngectomy and modified radical bilateral neck dissection. All sentinel nodes and removed non-sentinel nodes were examined by hematoxylin and eosin (H&E) staining. Results: Ten patients with laryngeal carcinoma were included. At least one sentinel node could be detected in five patients (bilateral nodes in four patients). One patient had pathologically involved sentinel and non-sentinel nodes (no false-negative cases). Conclusion: Sentinel node mapping in laryngeal carcinoma is technically feasible using an intra-operative radiotracer injection. In order to evaluate the relationship of T-stage and the laterality of the tumor with accuracy, larger studies are needed. |
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| نویسندگان مقاله |
احسان خدیوی | ehsan khadivi
sinus and surgical endoscopic research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
مریم دقیقی | maryam daghighi
sinus and surgical endoscopic research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
کامران خازنی | kamran khazani
sinus and surgical endoscopic research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
وحید رضا دباغ کاخکی | vahid reza dabbagh kakhki
nuclear medicine research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
لیلی zarifmahmoudi | leili zarifmahmoudi
nuclear medicine research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
رامین صادقی | ramin sadeghi
nuclear medicine research center, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
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| نشانی اینترنتی |
http://ijorl.mums.ac.ir/article_4418.html |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/11/article-11-80946.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original |
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