Iranian Journal of Otorhinolaryngology، جلد ۳۰، شماره ۱، صفحات ۵۵-۵۹

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عنوان انگلیسی Mandibular Involvement in Recurrent Multifocal Osteomyelitis Associated with SAPHO Syndrome
چکیده انگلیسی مقاله Introduction: SAPHO syndrome is defined as the association of a group of rare sterile osteoarticular disorders and inflammatory skin diseases whose etiology, although not yet determined, probably involves genetic, immunological and infectious mechanisms. The recurrent multifocal osteomyelitis, an inflammatory disease, can be associated with this syndrome even as a single event.  Case Report: A case of a young female patient, with a definite diagnosis of SAPHO and an inflammatory mandibular atypical disease for which therapeutic options with immunosuppressants were being used, is reported. The adverse evolution of the clinical conditions led to the hypothesis that the patient suffered from associated mandibular odontogenic bacterial osteomyelitis. The extraction of all teeth was recommended. After our evaluation, we recommended a conservative treatment, and after 2 months of treatment with an endovenous antibiotic, the patient showed improvement of clinical and laboratory results.  Conclusion: Early diagnosis is necessary to avoid successive and unnecessary tooth loss in the treatment of chronic osteomyelitis mandibular. 
کلیدواژه‌های انگلیسی مقاله Mandibular involvement, Osteomyelitis, SAPHO syndrome

نویسندگان مقاله igor moreira hazboun | igor moreira hazboun
department of otolaryngology head and neck, state university of campinas, faculty of medical sciences, campinas, sao paulo, brazil.


thiago pires brito | thiago pires brito
department of otolaryngology head and neck, state university of campinas, faculty of medical sciences, campinas, sao paulo, brazil.


ونسا gonçalves سیلوا | vanessa gonçalves silva
department of otolaryngology head and neck, state university of campinas, faculty of medical sciences, campinas, sao paulo, brazil.


کارلوس eduardo monteiro zappelini | carlos eduardo monteiro zappelini
department of otolaryngology head and neck, state university of campinas, faculty of medical sciences, campinas, sao paulo, brazil.


leopoldo نظام الدین pfeilsticker | leopoldo nizam pfeilsticker
otorhinolaryngologist, coordinator of ambulatory surgery and maxillofacial traumatology, state university of campinas, faculty of medical sciences, sao paulo, brazil.



نشانی اینترنتی http://ijorl.mums.ac.ir/article_10048.html
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نوع مقاله منتشر شده Case Report
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