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Iranian Journal of Basic Medical Sciences، جلد ۱۸، شماره ۱۲، صفحات ۱۲۴۵-۱۲۵۲
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Improvement effect of Lycium barbarum polysaccharide on sub-health mice |
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| چکیده انگلیسی مقاله |
Objective(s):Sub-health has been described as a chronic condition of unexplained deteriorated physiological function, which falls between health and illness. In the present study, we evaluated the effects of Lycium barbarum polysaccharide (LBP), a polysaccharide fraction purified from Lycium barbarum (L. barbarum) on the sub-health mice. Materials and Methods:The sub-health model mice were built through compound factors. The mice were given intragastric administration of LBP at low dose (50 mg•kg-1) and high dose (100 mg•kg-1), respectively. After LBP treatment for 4 weeks, the antioxidant ability, enhancing immune function and anti-fatigue activity were detected. Results:The results showed that LBP could enhance antioxidant ability in sub-health mice. LBP could effectively improve immunity of sub-health mice and protect the immune organs, such as thymus. In addition, LBP showed anti-fatigue ability in sub-health mice. Conclusion:LBP could improve sub-health state caused from composite factor through three aspects, such as increasing antioxidant ability, promoting T lymphocyte proliferation, inhibiting thymus lymphocyte apoptosis, and alleviating fatigue. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
روی zhao | rui zhao
department of pharmaceutical engineering, college of life science amp;amp; biotechnology, heilongjiang august first land reclamation university, daqing high-tech industrial development zone, 163319, p.r. china
wenli hao | wenli hao
department of pharmaceutical engineering, college of life science amp;amp; biotechnology, heilongjiang bayi agricultural university, daqing high-tech industrial development zone, 163319, p.r. china
baoling ma | baoling ma
department of physical education, hebei normal university of science and technology, 360 hebei street, qinhuangdao 066004, p.r. china
zhibao chen | zhibao chen
department of pharmaceutical engineering, college of life science amp;amp; biotechnology, heilongjiang bayi agricultural university, daqing high-tech industrial development zone, 163319, p.r. china
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| نشانی اینترنتی |
http://ijbms.mums.ac.ir/article_6281.html |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/87/article-87-45157.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original Article |
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