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Iranian Journal of Otorhinolaryngology، جلد ۲۹، شماره ۲، صفحات ۶۹-۷۴
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
The Effect of Topical Tranexamic Acid on Bleeding Reduction during Functional Endoscopic Sinus Surgery |
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| چکیده انگلیسی مقاله |
Introduction:Bleeding is a common concern during functional endoscopic sinus surgery (FESS) that can increase the risk of damage to adjacent vital elements by reducing the surgeon’s field of view. This study aimed to explore the efficacy of topical tranexamic acid in reducing intraoperative bleeding. Materials and Methods:This double-blind, randomized clinical trial was conducted in 60 patients with chronic rhinosinusitis with polyposis (CRSwP) who underwent FESS. Patients were randomly divided into two groups; tranexamic or salinetreatment. During surgery, normal saline (400 mL) or tranexamic acid (2 g) in normal saline with a total volume of 400 mL were used in the saline and tranexamic groups, respectively, for irrigation and suctioning. The surgeons’ assessment of field of view during surgery and intraoperative blood loss were recorded. Results:Mean blood loss was 254.13 mL in the saline group and 235.6 mL in the tranexamic group (P=0.31). No statistically significant differences between the two groups were found in terms of other investigated variables, such as surgical field quality based on Boezzart’s scale (P=0.30), surgeon satisfaction based on a Likert scale (P=0.54), or duration of surgery (P=0.22). Conclusion:Use of tranexamic acid (2 g in 400 mL normal saline) through washing of the nasal mucosa during FESS did not significantly reduce blood loss or improve the surgical field of view. Further studies with larger sample sizes and higher drug concentrations, and using other methods of administration, such as spraying or applying pledgets soaked in tranexamic acid, are recommended. |
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| نویسندگان مقاله |
حسین محمودی | hosein mahmoudi
otorhinolaryngology research center, shahid sadoughi university of medical sciences, yazd, iran
محمد حسین برادران فر | mohamad hosein baradaran far
otorhinolaryngology research center, shahid sadoughi university of medical sciences, yazd, iran
نسیم بهنیا فرد | nasim behnia fard
otorhinolaryngology research center, shahid sadoughi university of medical sciences, yazd, iran
محمد حسین داد gar نیا | mohamad hosein dad gar nia
otorhinolaryngology research center, shahid sadoughi university of medical sciences, yazd, iran
سعید atigheh chi | saeid atigheh chi
otorhinolaryngology research center, shahid sadoughi university of medical sciences, yazd, iran
وحید زند | vahid zand
otorhinolaryngology research center, shahid sadoughi university of medical sciences, yazd, iran
امین برادران فر | amin baradaran far
medical student, iran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
صدیقه وزیری بزرگ | sedigheh vaziri bozorg
otorhinolaryngology research center, shahid sadoughi university of medical sciences, yazd, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)
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| نشانی اینترنتی |
http://ijorl.mums.ac.ir/article_8286.html |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/11/article-11-326414.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
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