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Anatomical Sciences Journal، جلد ۱۹، شماره ۱، صفحات ۰-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| عنوان انگلیسی |
Morphometrical Evaluation of Corpus Callosum Using Mid-Sagittal Brain MRI Images in Patients With Relapsing-Remitting Multiple Sclerosis Referred to Besat Hospital in Hamadan from April 2011 To April 2021; A Retrospective Study |
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| چکیده انگلیسی مقاله |
Introduction: Corpus callosum (CC) as an intracranial organ is located in midline of cerebrum communicating both right and left hemispheres. CC undergoes morphological changes in multiple sclerosis (MS). Since the morphometrical changes of organs are directly associated with geographical regions, thus the aim of this study was to investigate the morphological alteration of CC in patients with relapsing-remitting MS in Hamadan (Iran) in a retrospective study from April 2011 to April 2021. Materials and Methods: Following conduction of inclusion and exclusion criteria, respectively 54 and 128 Brain MRI images of RRMS patients and healthy individuals were examined morphologically using PmsDICOMViewer software. Two main morphological indices of area (mm2) and longitudinal (mm) parameters were examined in midsagittal sections of Brain MRI images, including the area of CC (ACC) and associated segments, length of CC (LCC) and height of CC (HCC). Finally, the data were analysed by SPSS software (v. 19). P< 0.05 was considered as significancy level and data were presented as mean±SEM. Results: Following MS onset, total area of CC (ACC) was decreased significantly (p< 0.05) in MS patients than control. Also, the area of rosterum/genu (ARG) and area of anterior half midbody of CC (AAMB) showed significant (p< 0.05) incremental and decrimental trends, respectively. In other indices, no significant (p>0.05) differences were detected. Conclusion: Morphometrical measurements of CC are associated with the presence of MS. By the assessment of the anterior half of CC in brain MRI images (ARG and AAMB), the diagnosis of MS can be occurred. Thus, the results of investigation can be proposed as criteria for radiological confirmation of MS diseaese. |
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| کلیدواژه‌های انگلیسی مقاله |
Multiple Sclerosis, Corpus Callosum, Magnetic Resonance Imaging, Morphology, Hamadan, Retrospective |
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| نویسندگان مقاله |
| Fatemeh Zohreh-Vand
Member of Research Committee, Medical School, Hamadan University of Medical Sciences, Hamadan, Iran.
| Mehrdokht Mazdeh
Department of Neurology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
| Leili Tapak
Department of Biostatistics, School of Health, Hamadan University of Medical Sciences, Hamadan, Iran.
| Seyed Kamaledin Hadei
Department of Radiology, School of Medicine, Farshchian Cardiovascular Subspecialty Medical Center, Hamadan University of Medical Sciences, Hamadan, Iran.
| Mohammad Bahiraei
Department of Radiology, Besat Hospital, Hamadan University of Medical Sciences, Hamadan, Iran.
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| نشانی اینترنتی |
http://anatomyjournal.ir/browse.php?a_code=A-10-310-2&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Morphometry |
| نوع مقاله منتشر شده |
Original |
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