Journal of Family and Reproductive Health، جلد ۱۶، شماره ۲، صفحات ۱۳۲-۱۳۸

عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله

عنوان انگلیسی Concurrent Lead and Noise Exposure Effects on Testicular Tissue of Rat: An Experimental Study
چکیده انگلیسی مقاله Objective: Environmental stressors such as physical and chemical factors can have a destructive testicular function. The present study aimed to determine the effect of concomitant exposure to lead and noise on testicular tissue in male rats. Materials and methods: Twenty male Wistar rats (250-300 g, 12-13wk) were divided into four groups (n=5/each): 1) Control group, 2) Lead group treated with 4 mg/kg lead acetate by gavage for 30 days, 3) Noise group exposed to 4 kHz octave band at 105 dBA for eight hrs./ day for 30 days, and 4) the exposed group to lead plus noise concurrently. The testes' weight was measured, and testes abnormalities were assessed after staining with Hematoxylin and Eosin. Results: The results showed that the weight of testes in experimental groups was significantly decreased compared with the control group (p<0.0001). Also indicated edema, degeneration and necrotic cell debris in the lumen, congestion and atrophy of seminiferous tubule in rat testes tissue due to sub-acute exposure to lead and noise. Conclusion: Exposure to 105 dB and lead can cause damage to the seminiferous tubules, intubation edema, and testicular weight loss compared to control. We also found that simultaneous exposure to noise and lead could have more detrimental effects on testicular histology and weight than others.
کلیدواژه‌های انگلیسی مقاله

نویسندگان مقاله | Batol Masruri
Student Research Committee, School of Health, Iran University of Medical Sciences, Tehran, Iran


| Iraj Alimohammadi
Department of Occupational Health Engineering, School of Health, Iran University of Medical Sciences, Tehran, Iran


| Mohammad Reza Abyaz
Department of Pathology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran


| Nargess Moghadasi
Department of Occupational Health Engineering, School of Health, Iran University of Medical Sciences, Tehran, Iran


| Parvaneh Yekzamani
Department of Occupational Health Engineering, School of Health, Iran University of Medical Sciences, Tehran, Iran


| Baharak Mohammadzadeh Asl
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Nooshin Asadmasjedi
Department of Medical Laboratory Sciences, School of Paramedical Sciences, Dezful University of Medical Sciences, Dezful, Iran


| Azadeh Ashtarinezhad
Department of Occupational Health Engineering, School of Health, Iran University of Medical Sciences, Tehran, Iran



نشانی اینترنتی https://jfrh.tums.ac.ir/index.php/jfrh/article/view/1948
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات