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Iranian Journal of Basic Medical Sciences، جلد ۲۴، شماره ۸، صفحات ۱۰۱۴-۱۰۲۲
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Thymoquinone against infectious diseases: Perspectives in recent pandemics and future therapeutics |
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| چکیده انگلیسی مقاله |
The recent pandemics caused by coronavirus infections have become major challenges in 21st century human health. Scientists are struggling hard to develop a complete cure for infectious diseases, for example, drugs or vaccines against these deadly infectious diseases. We have searched papers on thymoquinone (TQ) and its effects on different infectious diseases in databases like Pubmed, Web of Science, Scopus, and Google Scholar, and reviewed them in this study. To date research suggests that natural products may become a potential therapeutic option for their prodigious anti-viral or anti-microbial effects on infectious diseases. TQ, a natural phytochemical from black seeds, is known for its health-beneficial activities against several diseases, including infections. It is evident from different in vitro and in vivo studies that TQ is effective against tuberculosis, influenza, dengue, Ebola, Zika, hepatitis, malaria, HIV, and even recent pandemics caused by severe acute respiratory syndrome of coronaviruses (SARS-CoV and SARS-CoV-2). In these cases, the molecular mechanism of TQ is partly clear but mostly obscure. In this review article, we have discussed the role of TQ against different infectious diseases, including COVID-19, and also critically reviewed the future use of TQ use to fight against infectious diseases. |
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| کلیدواژه‌های انگلیسی مقاله |
Antimicrobial natural, products Future therapeutics Infectious disease SARS, CoV Thymoquinone |
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| نویسندگان مقاله |
| Mousumi Tania
Research Division of Nature Study Society of Bangladesh, Dhaka, Bangladesh|Division of Molecular Cancer, Red Green Research Center, Dhaka, Bangladesh
| Asaduzzaman Asad
Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka, Bangladesh
| Tian Li
The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou, Sichuan, China
| Md. Shariful Islam
Department of Biochemistry and Molecular Biology, Tejgaon College, National University, Dhaka, Bangladesh
| Shad Bin Islam
Bachelor in Medicine and Surgery Program, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China
| Md. Munnaf Hossen
Department of Immunology, Health Science Center, Shenzhen, University, Shenzhen, Guangdong, China
| Mizanur Rahman Bhuiyan
Research Division of Nature Study Society of Bangladesh, Dhaka, Bangladesh
| Md. Asaduzzaman Khan
The Research Center for Preclinical Medicine, Southwest Medical University, Luzhou, Sichuan, China
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| نشانی اینترنتی |
https://ijbms.mums.ac.ir/article_18423.html |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Review Article |
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