Anatomical Sciences Journal، جلد ۲، شماره ۱، صفحات ۴۷-۵۴

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عنوان انگلیسی Sexual Dimorphism in Surface Anatomical Parameters of Human Cerebral Cortex in Different Lebes in Normal and Neurodegenerative Subjects: a Stereological and Macroscopical Study
چکیده انگلیسی مقاله Purpose: This study sought to determine sex differences in surface anatomical parameters (thickness and surface areas) of human cerebral cortex in different lobes of the left hemisphere in normal right-handed subjects and right-handed subjects suffering from Alzheimer and Parkinson's diseases. Materials and Methods: This cross-sectional descriptive study was performed on 72 normal human brains (38 males, 34 females); 11 brains suffered from Alzheimer (4 males, 7 females), and 13 brains suffered from Parkinson's disease (9 males, 4 females). The age of the males and females in each group was similar.The right hemisphere of each brain was used for neuropathological diagnosis, and the left one was used for morphometrical analysis. The stmation of thickness and surface areas in the cerebral cortex of different lobes of the left hemisphere was performed on photographs of 5mm serial coronal sections of this hemisphere with a linear grid based on unbiased sterelogical method. The results were analyzed by t-student and non-parametrical Mann- Whitney statistical tests. Results: The thickness of the left parietal cortex was significantly smaller in healthy right-handed women than in men (p=0.02). The thickness of cortex in other lobes of the left hemisphere showed no significant sexual difference in healthy right-handed subjects; however, there was a tendency (0.05
کلیدواژه‌های انگلیسی مقاله Sexual dimorphism, Surface anatomy, Cerebral cortex, Alzheimer, Parkinson

نویسندگان مقاله | Hosein Haghir
Anatomy Department, Mashhad Medical Science University, Mashhad, Iran.


| Parviz Mehr Aein



نشانی اینترنتی http://anatomyjournal.ir/browse.php?a_code=A-10-304-58&slc_lang=fa&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده fa
موضوعات مقاله منتشر شده Morphometry
نوع مقاله منتشر شده Original
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