Iranian Journal of Otorhinolaryngology، جلد ۳۳، شماره ۲، صفحات ۱۱۹-۱۲۵

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عنوان انگلیسی IgG4-Related Laryngeal Disease as a Possible Cause of Idiopathic Subglottic Stenosis: A Case Report
چکیده انگلیسی مقاله Introduction: Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibro-inflammatory disorder.  Laryngotracheal manifestation is very rare; therefore, it is usually associated with complex diagnostic and therapeutic problems.   Case Report: Herein, we report the case of a 35-year-old woman with idiopathic subglottic stenosis (ISGS) treated with one-step laryngotracheal reconstruction surgery. Postoperatively, the lesion was found to be a part of the IgG4-RD spectrum. Objective and subjective phoniatric tests, spirometry, and Quality of Life Questionnaire were used for the evaluation of postoperative functional results. Slide laryngotracheoplasty as a one-step surgery without stenting and tracheostomy ensured a sufficiently wide subglottic space with no adverse effect on voice quality. During a follow-up period of 22 months, endoscopy and computed tomography scan revealed no significant restenosis. The patient was able to return to premorbid activities of daily living without any further medical treatment. Conclusion: The laryngeal involvement of IgG4-RD is uncommon; however, it is a manifestation that should be included in the differential diagnosis of subglottic stenoses (SGS). Furthermore, subglottic IgG4-RD might be a potential etiological factor of ISGS and acquired airway stenosis after short-term intubation. Slide laryngotracheoplasty might be a favorable solution without stenting and tracheostomy even in special cases of SGS.
کلیدواژه‌های انگلیسی مقاله Fibro-inflammatory disorder, Idiopathic subglottic stenosis, IgG4, Laryngotracheoplasty

نویسندگان مقاله | Ádám Bach
Department of Otorhinolaryngology & Head- Neck Surgery, University of Szeged; Tisza Lajos krt. 111., 6725, Szeged, Hungary.


| Andrea Ambrus
Department of Otorhinolaryngology & Head- Neck Surgery, University of Szeged; Tisza Lajos krt. 111., 6725, Szeged, Hungary.


| Béla Iványi
Department of Pathology, University of Szeged, Állomás u. 2, 6725, Szeged, Hungary.


| Zoltán Tóbiás
Department of Otorhinolaryngology & Head- Neck Surgery, University of Szeged; Tisza Lajos krt. 111., 6725, Szeged, Hungary.


| Gholam Hossein Alim Marvasti
Department of Otorhinolaryngology & Head- Neck Surgery, University of Szeged; Tisza Lajos krt. 111., 6725, Szeged, Hungary.


| László Rovó
Department of Otorhinolaryngology & Head- Neck Surgery, University of Szeged; Tisza Lajos krt. 111., 6725, Szeged, Hungary.



نشانی اینترنتی https://ijorl.mums.ac.ir/article_17598.html
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نوع مقاله منتشر شده Case Report
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