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Iranian Journal of Basic Medical Sciences، جلد ۲۳، شماره ۲، صفحات ۲۲۴-۲۳۵
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عنوان فارسی |
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چکیده فارسی مقاله |
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کلیدواژههای فارسی مقاله |
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عنوان انگلیسی |
Pharmacological and computational evaluation of Sapodilla and its constituents for therapeutic potential in hyperactive gastrointestinal disorders |
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چکیده انگلیسی مقاله |
Objective(s): This study was designed to investigate various gastrointestinal effects of Manilkara zapota (Sapodilla), exploring its anti-diarrheal, anti-secretary, anti-spasmodic, anti-ulcer and anti-motility potential.Materials and Methods: Antidiarrheal and anti-secretary activities were investigated using castor oil induced diarrhea and castor oil induced fluid accumulation. Isolated rabbit jejunum tissues (antispasmodic) were employed for in vitro experiments. Antiulcer, antimotility and molecular docking were performed using ethanol-HCl induced ulcer assay, charcoal meal transit time and Auto Doc Vina.Results: Mz.Cr exhibited protection against castor oil-induced diarrhea (P |
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کلیدواژههای انگلیسی مقاله |
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نویسندگان مقاله |
| Muhammad Bilal Riaz Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad
| Arif-ullah Khan Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad
| Neelam Gul Qazi Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad
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نشانی اینترنتی |
http://ijbms.mums.ac.ir/article_14287.html |
فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/87/article-87-2144619.pdf |
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زبان مقاله منتشر شده |
en |
موضوعات مقاله منتشر شده |
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نوع مقاله منتشر شده |
Original Article |
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