Iranian Journal of Basic Medical Sciences، جلد ۲۳، شماره ۱، صفحات ۱۰۲-۱۱۰
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عنوان انگلیسی Protective effect of crocin on electromagnetic field-induced testicular damage, heat shock protein A2 expression in male BALB/c mice
چکیده انگلیسی مقاله Objective(s): Exposure to electromagnetic fields (EMF) emitted from mobile phones may cause a deleterious effect on human health and may affect the male reproductive system. Crocin, a carotenoid isolated from Crocus Sativus L. (Saffron), is a phar‌macologically active component of saffron. So, this study was conducted to investigate the protective effect of crocin on the male reproductive system of 60 day old mice after EMF exposure. Materials and Methods: Twenty-four male Balb/c mice were randomly divided into 4 groups: 1. Em group (2100 MHZ); 2. Cr group (50 mg/kg); 3. Em+Cr group (2100 MHZ+50 mg/kg), and 4. Control group. Sperm parameters (count, and abnormal percent), testis weight index, testis volume, seminiferous tubule diam‌eter, germinal epithelium thickness, LH, FSH and testosterone serum level, testicular Heat shock protein A2 (HspA2) immunoreactivity, and apoptosis were evaluated.Results: HspA2 immunoreactivity, apoptosis in the germinal epithelium and abnormal sperm were increased in Em group compared with the control group (P
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نویسندگان مقاله | shayan Vafaei
Department of Anatomy and Cell Biology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran


| Fatemeh Motejaded
Department of Anatomy and Cell Biology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran


| Alireza Ebrahimzadeh-bideskan
Department of Anatomy and Cell Biology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran|Microanatomy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
نشانی اینترنتی http://ijbms.mums.ac.ir/article_14238.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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