چکیده انگلیسی مقاله |
Aims: Diagnosing fetal disorders and abnormalities in the early stages of pregnancy can prevent future adverse conditions for the infant and his/her family. This study aimed to evaluate the sensitivity and specificity of the first- and second-trimester screening tests for identifying fetal chromosomal disorders in pregnant women. Materials and Methods: This retrospective cohort study was performed at Yas Hospital. In the present study, all pregnant women, who referred to Yas Hospital for their first- and second-trimester screening tests, were studied from 2015 to 2017. Findings: A total of 960 pregnant women participated in this study. The participants' mean age was 31.07± 0.17 years. Most of the participants (43.4%) were primigravida. The sensitivity of the first-trimester screening test was 70%, and its specificity was 80.3%. The sensitivity and specificity of the second-trimester screening test were 45% and 94.5%, respectively. Conclusion: Despite recent advances in the prenatal field, the accuracy of screening tests may still vary depending on maternal age and other existing characteristics. Consequently, in parents consulting, the possibility of false positives and negatives should be considered in the tests. |
نویسندگان مقاله |
| Mahboobeh Shirazi Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
| Soheila Sarmadi Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
| Shirin Niromanesh Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
| Fatemeh Rahimi Sharbaf Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
| Behrokh Sahebdel Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
| Fatemeh Golshahi Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
| Leila Asadi School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
| Maedeh Rahmanzadeh Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
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