Journal of Obstetrics, Gynecology and Cancer Research، جلد ۴، شماره ۱، صفحات ۰-۰

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عنوان انگلیسی Assessment of the Sensitivity and Specificity of Screening Tests Performed in the First and Second Trimester in the Pregnant Women
چکیده انگلیسی مقاله Aims: Diagnosing fetal disorders and abnormalities in the early stages of pregnancy can prevent future adverse conditions for the infant and his/her family. This study aimed to evaluate the sensitivity and specificity of the first- and second-trimester screening tests for identifying fetal chromosomal disorders in pregnant women. Materials and Methods: This retrospective cohort study was performed at Yas Hospital. In the present study, all pregnant women, who referred to Yas Hospital for their first- and second-trimester screening tests, were studied from 2015 to 2017. Findings: A total of 960 pregnant women participated in this study. The participants' mean age was 31.07± 0.17 years. Most of the participants (43.4%) were primigravida. The sensitivity of the first-trimester screening test was 70%, and its specificity was 80.3%. The sensitivity and specificity of the second-trimester screening test were 45% and 94.5%, respectively. Conclusion: Despite recent advances in the prenatal field, the accuracy of screening tests may still vary depending on maternal age and other existing characteristics. Consequently, in parents consulting, the possibility of false positives and negatives should be considered in the tests.  
کلیدواژه‌های انگلیسی مقاله Screening, Aneuploidy, Pregnancy, Sensitivity, Specificity

نویسندگان مقاله | Mahboobeh Shirazi
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran


| Soheila Sarmadi
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran


| Shirin Niromanesh
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran


| Fatemeh Rahimi Sharbaf
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran


| Behrokh Sahebdel
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran


| Fatemeh Golshahi
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran


| Leila Asadi
School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran


| Maedeh Rahmanzadeh
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran



نشانی اینترنتی http://jogcr.com/browse.php?a_code=A-10-86-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Maternal Fetal Medicine
نوع مقاله منتشر شده پژوهشی اصیل
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