|
|
Journal of Dentistry, Shiraz University of Medical Sciences، جلد ۱۷، شماره ۱، صفحات ۴۳-۰
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Histological Evaluation of Wound Healing Process after Photodynamic Therapy of Rat Oral Mucosal Ulcer |
|
| چکیده انگلیسی مقاله |
Statement of the Problem: When the body defense is compromised, wounds can act as a route for entrance and colonization of microorganisms in the body. Photodynamic therapy with methylene blue is known as a promising antimicrobial modality. Purpose: The present study aimed to investigate the effects of this procedure on wound healing processes. Materials and Method: In this experimental study, 48 male Wistar rats were recruited. Experimental wounds were surgically made on their buccal mucosa. Based on the treatment modality, they were divided into 3 groups (n=16) of control (CG), laser (LG), photosensitizer+ laser (PLG) by methylene blue (MB). The treatment procedure in the two latter groups was done in days 1-4 and 6-9. After sacrificing on 2, 4, 7 and 14-day follow-ups, the microscopic grade of healing of the wounds was assigned on each interval according to histological grading criteria. Results: A qualitative result was obtained that showed a healing progression in PLG at day 2 of follow-up. At day 4 of follow-up, no difference was seen in healing stage among the groups. However on day 7 of follow-up, samples of the LG showed a lower degree of healing compared with the other two groups. Likewise, on day 14 of follow- up, both PLG and LG showed lower degree of healing than CG. Conclusion: This study qualitatively showed that MB- mediated photodynamic therapy would have an inhibitory effect on healing process after 14 days of the wound creation. Key Words: Laser; Methylene Blue; Photodynamic Therapy; Wound Healing |
|
| کلیدواژه‌های انگلیسی مقاله |
|
|
| نویسندگان مقاله |
پرویز دیهیمی | parviz deyhimi
torabinejad dental research center, dept. of oral and maxillofacial pathology, school of dentistry, isfahan university of medical sciences, isfahan, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)
حیدر خادمی | heidar khademi
torabinejad dental research center, dept. of oral and maxillofacial diseases, school of dentistry, isfahan university of medical sciences, isfahan, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)
رضا بیرنگ | reza birang
torabinejad dental research center, dept. of periodontology, school of dentistry, isfahan university of medical sciences, isfahan, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)
محمد آخوندزاده | mohammad akhoondzadeh
dept. of oral and maxillofacial diseases, school of dentistry, boushehr university of medical sciences, boushehr, iran.
|
|
| نشانی اینترنتی |
http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/986 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/331/article-331-117441.pdf |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
|
| نوع مقاله منتشر شده |
Original Articles |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|