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Journal of Family and Reproductive Health، جلد ۶، شماره ۳، صفحات ۹۵-۹۸
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عنوان انگلیسی Relation between Fluoxetine and Menstrual Cycle Disorders
چکیده انگلیسی مقاله Objective: To investigate the effect of fluoxetine as an SSRI on menstrual disorders. Materials and methods: In this cross-sectional study 200 women referring to the Islamic Azad University affiliated hospitals during March 2011- March 2010 were divided into 4 groups. All included patients in this study had the chief complaint of mood disorders in peri- menstrual period. All patients received daily vitamin B6 tablets as primitive treatment. In groups A, B and C patients also received daily doses of 10 mg, 20 mg and 40 mg of fluoxetine respectively for 6 months and in group D as the control group fluoxetine was not given. Data were analyzed by spss18 statistical software. Significant difference was set at p< 0.05. Results: In the groups receiving fluoxetine (groups A - C) 34 patients and in control group 5 patients showed irregular menstruation started during fluoxetine administration and following 3 months. Significant difference with p< 0.05 was found regarding the incidence of menstrual irregularity between groups with and without fluoxetine prescription. Conclusion: Fluoxetine consumption leads to increased incidence of menstrual irregularity compared to the control group. The incidence increases with increasing dosage of the drug.
کلیدواژه‌های انگلیسی مقاله Fluoxetine,SSRI,Menstrual Cycle disorders
نویسندگان مقاله ژیلا امیرخانی | zhila amirkhani
islamic azad university research center, medical tehran branch, tehran, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

میثم اخلاق دوست | meisam akhlaghdoust
functional neurosurgery research center, shaheed beheshti university of medical sciences, tehran, ir

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

گلاره صالحی | gelareh salehi
young researchers club, tehran medical branch, islamic azad university, tehran, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

احسان جانقلی | ehsan jangholi
young researchers club, tehran medical branch, islamic azad university, tehran, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

محمدرضا صادقی | mohamadreza sadeghi
students amp;amp; 039; research committee, tehran medical branch, islamic azad university, tehran, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

فریما قناعت | farima ghenaat
students amp;amp; 039; research committee, tehran medical branch, islamic azad university, tehran, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

نسا ضربتی | nesa zarbati
department of medical genetics amp;amp; sarem cell research center, sarem hospital, tehran, iran


مینا جعفرآبادی | mina jafarabadi
reproductive health research center, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://jfrh.tums.ac.ir/index.php/jfrh/article/view/150
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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