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درباره پایگاه
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JCR 2016
جستجوی مقالات
چهارشنبه 10 دی 1404
Iranian Journal of Immunology
، جلد ۱۱، شماره ۴، صفحات ۲۵۹-۲۶۸
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Analysis of Serum Cytokine Levels in Larynx Squamous Cell Carcinoma and Dysplasia Patients
چکیده انگلیسی مقاله
Background: Although the imbalance of cytokines in Head and Neck Squamous Cell Carcinoma (HNSCC) is well known, there is scarce data regarding its occurrence during dysplasia, before the malignant transformation. Objective: To determine whether laryngeal dysplasia patients show a different cytokine profile than patients with cancer and healthy controls. Methods: Seventeen newly diagnosed, untreated larynx squamous cell carcinoma (SCC) and six laryngeal dysplasia patients as well as 22 healthy controls were analyzed for circulating cytokines. A flowcytometry Th1/Th2 cytokine array kit was used to quantitatively measure Interleukin-2 (IL-2), IL-4, IL-6, IL-10, Tumor Necrosis Factor-α (TNF-α) and Interferon-γ (IFN-γ) levels. Additionally, IL-8 levels were determined through ELISA. Results: IL-6, IL-8 and IL-10 were determined to be statistically increased in SCC patients (p
کلیدواژههای انگلیسی مقاله
Bead Array,Cytokine,Dysplasia,HNSCC,Larynxm Carcinoma
نویسندگان مقاله
mete eyigor |
akdeniz university medical faculty, department of medical microbiology
hulya eyigor |
department of ent head and neck surgery, antalya education and research hospital
ustun osma |
department of ent head and neck surgery, antalya education and research hospital
mustafadeniz یلماز |
department of ent head and neck surgery, antalya education and research hospital
nuray erin |
akdeniz university medical faculty, department of medical pharmacology
omer tarik selcuk | omer tarik
department of ent head and neck surgery, antalya education and research hospital
cem sezer |
department of pathology, antalya education and research hospital, antalya, turkey
مرال gultekin |
akdeniz university medical faculty, department of medical microbiology
سعدی koksoy |
akdeniz university medical faculty, department of medical microbiology
نشانی اینترنتی
http://iji.sums.ac.ir/article_16786_c6e88da9f558d773a7abdfd40659951d.pdf
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زبان مقاله منتشر شده
en
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