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Journal of Dentistry, Shiraz University of Medical Sciences، جلد ۱۹، شماره ۳، صفحات ۱۸۹-۰
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی Postoperative Pain Management after Impacted Third Molar Surgery with Preoperative Oral Lamotrigine, a Randomized, Double-blind, Placebo-Controlled Trial
چکیده انگلیسی مقاله Statement of the Problem: Extraction of the impacted third molar is often associated with severe postoperative pains, management of which are a big challenge. Lamotrigine is a new antiepileptic drug with pre-emptive analgesic properties, which is hypothesized to alleviate postoperative pain. Purpose: This study aimed to evaluate the efficacy of pre-operative administration of single oral 200 mg lamotrigine in reducing the postoperative pain of impacted third molar surgery. Materials and Method: In this randomized controlled trial, 100 adult patients were divided into two groups (n= 50) to receive either 200 mg oral lamotrigine or placebo 1 hour before the removal of impacted third molar. The patients were monitored for 4 hours in the recovery room and pain intensity was measured through visual analogue scale (VAS) for the next 12 hours at 30-minute intervals. The time and number of rescue analgesics used in 12 hours was also recorded. Results: Two groups were not statistically significantly different regarding the severity of postoperative pain. ( p = 0.512) Conclusion: Accordingly, pre-emptive administration of lamotrigine was not effective in diminishing the postoperative acute pain of impacted third molar extraction. Key Words Lamotrigine; Third Molar; Pain Management;
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نویسندگان مقاله | Hamed Modanloo
Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.


| Hamıdreza Eftekharıan
Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.


| Hamidreza Arabiun


نشانی اینترنتی http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/1828
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/331/article-331-817462.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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