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گوارش، جلد ۱۷، شماره ۳، صفحات ۱۸۳-۰
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عنوان انگلیسی Red Cell Distribution Width Levels and Disease Activity in Ulcerative Colitis
چکیده انگلیسی مقاله Background: The amount of literature concerning the implication of the red cell distribution width (RDW) in the assessment of ulcerative colitis (UC) activity is rather limited. The aim of this study is to investigate the potential role of RDW in the evaluation of UC disease activity. Materials and Methods: A total of 96 patients with UC and 51 age and sex-matched healthy volunteers were included in a cross-sectional study. Clinical disease activity was defined using the numerical Disease Activity Index (DAI). In addition to RDW, serum C-reactive protein (CRP) levels, erythrocyte sedimentation rates (ESR), and platelet counts (PLT) were measured. Results: AThere were 47 (about 49%) patients with that had active UC. The RDW was significantly higher in patients with UC than in controls (p=0.001) and active versus patients in remission (p‹0.001). RDW was significantly correlated with DAI scores, ESR, CRP and PLT in active patients. There was a significant correlation between RDW with DAI scores and CRP levels in patients who were in remission. Conclusion: RDW was elevated in UC patients in comparison with healthy controls and increased markedly in active disease. It was also strongly correlated with clinical disease activity scores and inflammatory parameters such as ESR and CRP. RDW, as a cost-effective tool, may be an additional parameter to assess disease activity in UC.
کلیدواژه‌های انگلیسی مقاله Ulcerative colitis,Disease activity,RDW
نویسندگان مقاله نسیم abedimanesh | nasim abedimanesh


بیت الله علیپور | beitullah alipour


محمدحسین صومی | mohammadhossein somi


علیرضا استادرحیمی | alireza ostadrahimi


سعید abedimanesh | saeed abedimanesh


محمد اصغری جعفرآبادی | mohammad asgharijafarabadi


علی اکبر موثق پور | aliakbar movassaghpour


نشانی اینترنتی http://www.govaresh.org/index.php/dd/article/view/1018
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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