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گوارش، جلد ۱۷، شماره ۳، صفحات ۱۴۲-۰
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عنوان انگلیسی Relation between Helicobacter pylori Infection with Thyroid Autoantibodies in Dyspeptic Patients
چکیده انگلیسی مقاله Background: Infections attributed to Helicobacter pylori ( H. pylori ) involve almost half of the world's population. One of the effects is auto-antibody induction and cross-reaction with numerous proteins in the body. As a result of its widespread prevalence and importance, this study evaluates the associations between H. pylori and thyroid auto-antibodies. Materials and Methods: This study enrolled 100 patients who were candidates for gastroesophageal endoscopies that referred to the Yazd Gastrointestinal Clinic. Patients underwent the following laboratory analyses: urease test, anti- H. pylori (IgG), TSH, T4, T3 and thyroid auto-antibodies (anti-thyroglobulin, anti-thyroid peroxides). Patients were divided into two groups of H. pylori positive and negative according to the results of the anti- H. pylori IgG and urease tests.. The level of thyroid auto-antibodies and thyroid function were compared between groups. Data were analyzed with chi-square and t-tests. SPSS software version 17 was used for data analysis. Results: Overall, 61% of patients were H. pylori positive. The mean anti-Thyroid peroxidase level in the H. pylori positive group was significantly more than the negative group ( p ‹0.01). In addition, 19.7% of H. pylori positive patients and 5.1% of H. pylori negative patients had positive anti-TPO levels, which the difference between both groups was significant ( p ‹0.04). There was no significant difference in thyroid function between the two groups. Conclusion: Although no significant difference in thyroid function was seen in the two groups more patients tested positive for anti- TPO levels in the H. pylori positive group, which was suggestive of thyroid auto-antibody induction by H. pylori
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نویسندگان مقاله محمدحسین آنتیک چی | mohammadhossein antikchi


حمید میرحسینی | hamid mirhosseini


مریم sadatsalami | maryam sadatsalami


رضا بیدکی | reza bidaki


امیدرضا حسینی | omidreza hosseini


علیرضا ملاعباسی | alireza mollaabasi


nasroola بشردوست | nasroola bashardoost


نشانی اینترنتی http://www.govaresh.org/index.php/dd/article/view/1019
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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