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Iranian Journal of Microbiology، جلد ۹، شماره ۵، صفحات ۲۷۷-۲۸۲

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عنوان انگلیسی A Study of prevalence of Shigella species and antimicrobial resistance patterns in paediatric medical center, Ahvaz, Iran
چکیده انگلیسی مقاله Background and Objectives: Shigella infections are one of the major causes of diarrhea worldwide, and especially in developing countries. Antimicrobial resistance has complicated the empirical treatment. The aim of this study was to define the clinical and antibiotic resistance patterns of Shigella gastroenteritis cases. Materials and Methods: Stool samples of patients with diarrhea and fever diagnosed with shigellosis were collected, from June 2013 to May 2014 at Abuzar Hospital, Iran. All samples were cultured for Shigella spp on selective and differential media. Shigella isolates were evaluated for antimicrobial resistance. Results: Among 193 Shigella isolates, S. flexneri (64.8%) was the predominant species followed by S. sonnei (32.6%). The most frequent antibiotic resistance observed, was towards co-trimoxazole (89%), ampicillin (77%) and ceftriaxone (51%) and the lowest resistance were seen in ciprofloxacin (1.5%), azithromycin (7%). Conclusion: Due to the high resistance to ceftriaxone, this drug is not recommended as an empirical therapy for shigellosis. However, azithromycin should be used as the first-line treatment for paediatric patients, suffering from shigellosis and ciprofloxacin can be used as an alternative.
کلیدواژه‌های انگلیسی مقاله Anti-microbial resistance,Shigella,Children

نویسندگان مقاله رویا نیک فر | roya nikfar
infectious and tropical diseases research center, health research institute, ahvaz jundishapur university of medical sciences, ahvaz, iran; department of pediatrics, aboozar children amp; 039;s hospital, ahvaz jundishapur university of medical sciences, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

احمد شمسی زاده | ahmad shamsizadeh
department of pediatrics, aboozar children amp; 039;s hospital, ahvaz jundishapur university of medical sciences, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

مرجان darbor | marjan darbor
infectious and tropical diseases research center, health research institute, ahvaz jundishapur university of medical sciences, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

سهیلا خاقانی | soheila khaghani
department of pediatrics, aboozar children amp; 039;s hospital, ahvaz jundishapur university of medical sciences, ahvaz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

مینا مقدم | mina moghaddam



نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/view/1297
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/91/article-91-568440.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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