این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Nanomedicine Journal، جلد ۵، شماره ۱، صفحات ۱۹-۲۶
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Antibacterial activity of nickel and nickel hydroxide nanoparticles against multidrug resistance K. pneumonia and E. coli isolated urinary tract
چکیده انگلیسی مقاله Objective(s): Antibacterial materials are so significant in the textile industry, water disinfection, medicine, and food packaging. Unfortunately, organic compounds for sterilization show toxicity to the human body; therefore, the interest in inorganic disinfectants such as metal oxide nanoparticles (NPs) is increasing. Materials and Methods: Nickel and nickel hydroxide nanoparticles (NiNPs and Ni(OH)2-NPs) were prepared and characterized by DLS, SEM, AFM and ATR. Antibacterial activity assay was carried by Spot on lawn method against two selected standard pathogenic bacteria such as E. coli (as Gram negative), S. aureus (as Gram positive) and multidrug resistance K. pneumonia and E. coli. Also the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined against two selected standard pathogenic bacteria and multidrug resistance K. pneumonia and E. coli. Results: The formation of the NiNPs and Ni(OH)2-NPs were confirmed by DLS, SEM, AFM and ATR. Antibacterial activity of nanoparticles were confirmed against two selected standard pathogenic bacteria such as E. coli and S. aureus. And also, NiNPs and Ni(OH)2-NPs revealed fair antibacterial effect against multidrug resistance K. pneumonia and E. coli based on MIC and MBC data. As well, the experimental data presented that the antibacterial activity of NiNPs was more than Ni(OH)2-NPs. Conclusion: Based on the achieved results, NiNPs and Ni(OH)2-NPs show antibacterial activity against clinical patients bacteria (multidrug resistance K. pneumonia and E. coli(. Finally, the NPs evaluated in this study have promising properties for applications as antiseptic agent for environment; however, further studies are warranted such as study toxicity NPs on normal human cell line and other clinical bacteria.
کلیدواژه‌های انگلیسی مقاله Antibacteial, NiNPs, Ni(OH)2, Nanoparticles, Pathogen
نویسندگان مقاله محبوبه میرحسینی | mahboubeh mirhosseini
department of biology, payame noor university, iran

سازمان اصلی تایید شده: دانشگاه پیام نور تهران (Payame noor university)

بهاره خیری هفشجانی | bahareh kheiri hafshejani
department of biology, payame noor university, iran

سازمان اصلی تایید شده: دانشگاه پیام نور تهران (Payame noor university)

فریبا دشتستانی | fariba dashtestani
department of biology, electronic branch, islamic azad university, tehran, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

فاطمه حکیمیان | fatemeh hakimian
institute of biochemistry and biophysics, university of tehran, tehran, iran

سازمان اصلی تایید شده: مرکز تحقیقات بیوشیمی و بیوفیزیک (Institute of biochemistry and biophysics)

بی بی فاطمه حقیرالسادات | bibi fatemeh haghirosadat
department of life science engineering, faculty of new sciences and technologies, university of tehran, tehran, iran

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

نشانی اینترنتی http://nmj.mums.ac.ir/article_10051.html
فایل مقاله دریافت فایل مقاله
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده مقاله پژوهشی
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات