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Nanomedicine Journal، جلد ۴، شماره ۳، صفحات ۱۷۷-۱۸۳
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عنوان انگلیسی Fabrication of hydroxyapatite-baghdadite nanocomposite scaffolds coated by PCL/Bioglass with polyurethane polymeric sponge technique
چکیده انگلیسی مقاله Objecttive (s): Silicate bioceramics like Baghdadite with chemical formula Ca3ZrSi2O9, has attracted the attention of researchers in biomedical field due to its remarkable in-vitro and in-vivo bioactivity and mechanical properties.Materials and Methods: Therefore, in the current study the baghdadite powder with Sol-Gel method was synthesized. Then, hydroxyapatite/Baghdadite (HA/Bagh) scaffolds were prepared by the replacing the polyurethane polymeric sponge technique. Afterwhile, the ceramic scaffolds were sintered at 1150ºC for 3 h. The prepared scaffold was then coated by polycaprolactone/bioglass (PCL/BG) polymer nanocomposite. Results: Bioactivity and biomineralization in the simulated body fluid (SBF) revealed that the nanocomposite scaffolds coate with PCL/BG had significant bioactivity properties. The morophology and microstructure investigation of soaked samples in SBF indicate that bone-like apatite formed on the surfaces. Also, ion release in SBF containing the scaffolds was measured by inductively coupled plasma (ICP) analysis. The nucleation positions of apatite crystals were areas with high silicon containing, Si+4 ion positions.Conclusion: The study indicates that scaffold containing 30 wt. % baghdadite had proper bioactivity behaviordue to its ability to form bone-like apatite on the surface of specimens.
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نویسندگان مقاله ابراهیم کرمیان | ebrahim karamian
advanced materials research center, faculty of materials engineering, najafabad branch, islamic azad university, najafabad, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

اکرم ناصحی | akram nasehi
advanced materials research center, faculty of materials engineering, najafabad branch, islamic azad university, najafabad, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

سعید صابر سمندری | saeed saber samandari
new technologies research center, amirkabir university of technology, tehran, iran

سازمان اصلی تایید شده: دانشگاه صنعتی امیرکبیر (Amirkabir university of technology)

امیرسالار خندان | amirsalar khandan
young researchers and elite club, khomeinishahr branch, islamic azad university, isfahan, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

نشانی اینترنتی http://nmj.mums.ac.ir/article_8959.html
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