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Iranian Journal of Microbiology، جلد ۴، شماره ۴، صفحات ۱۸۷-۱۹۰
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عنوان انگلیسی CO(2) Laser therapy versus cryotherapy in treatment of genital warts; a Randomized Controlled Trial (RCT).
چکیده انگلیسی مقاله Background and Objective: Genital warts, due to specific types of the human papillomavirus, have long been regarded as one of the most important causes of cervical cancer and one of the most common cause of Sexually Transmited Diseases (STDs). Over the years, it has been the focus of several studies in order to find the best effective approach to eradicate the virus, however there are still controversies regarding this matter. We compared efficacy of the two physical ablative therapies; Liquid Nitrogen and CO laser. Material and Methods: One hundred and sixty patients, with external genital warts, were divided into two groups. Each group consisted of 80 patients treated with CO -laser or cryotherapy. Clearance and recurrence rates were evaluated for 3months. Results: Complete clearance was achieved in 76 lesions (95%) treated by CO -laser and 37 lesions (46.2%) treated by cryotherapy which was significantly different (p < 0.001). In the CO -laser group, lesions required only one treatment to clear while in the cryotherapy group, lesions required two (12%) even up to three (12.2%) treatments for some patients to clear completely. Laser therapy was associated with less recurrence rate compared to cryotherapy (0.05% Vs 0.18%). Conclusion: Generally, the efficacy of CO laser treatment of external genital warts was approximately two fold greater than cryotherapy and it was associated with lower recurrence rate.
کلیدواژه‌های انگلیسی مقاله CO2 laser,Genital warts,Human Papillomavirus,cryotherapy
نویسندگان مقاله m عزیز جلالی | m azizjalali
skin and stem cell research center, tehran university of medical sciences, tehran, iran and department of dermatology, rasoul akram hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

gh غفارپور | gh ghaffarpour
skin and stem cell research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

b موسوی فرد | b mousavifard
skin and stem cell research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/view/675
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