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Iranian Journal of Microbiology، جلد ۵، شماره ۳، صفحات ۲۱۵-۲۱۹
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Screening of family members of patients with acute brucellosis in an endemic area of Iran.
چکیده انگلیسی مقاله Background and Objectives: Brucellosis is a zoonotic disease and it’s still endemic in Iran. There are some reports regarding brucellosis infection in family members sharing same risk factors and remain unrecognized. However , few studies on the importance of family screening are available. We aimed to screen household members of index cases with acute brucellosis for detecting additional unrecognized cases in central province of Iran. Patients and Methods: 163 family members of 50 index cases were enrolled in the study. Standard Tube Agglutination Test (STA) and 2-mercaptoethanol (2ME) agglutination were checked in all samples. A case with STA titer ≥ 1:80,2-mercaptoethanol (2ME) agglutination ≥ 40 and compatible signs and symptoms was considered positive for brucellosis. Results: 15 (9.2%) of family members were seropositive fo r Brucella agglutinin and among them, 8 (53.3%) were asymptomatic and 7 (46.7%) were symptomatic. STA titer ranged from 1:80 to 1:640 in seropositive members. 4 of the 15 seropositive cases who identified by screening came from one index case with 6 family members. All symptomatic seropositive cases treated for Brucella infection and recovered without any complications in 6 months follow up. Conclusion: On the basis of our data, family members of brucellosis patients are at risk of disease acquisition, and screening of household members provides an effective way for early diagnosis and prompt treatment. However cost benefit of screening should be evaluated to reach definite decision for the implementation of the screening as a nationwide program.
کلیدواژه‌های انگلیسی مقاله Acute Brucellosis,Family member,Index cases,Screening
نویسندگان مقاله معصومه صوفیان | masoomeh sofian
tuberculosis and pediatric infectious research center, arak university of medical sciences, arak, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (Arak university of medical sciences)

لیلا صفایی پور | leila safaeipour
arak university of medical sciences, arak, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (Arak university of medical sciences)

آرزو آقاخانی | arezoo aghakhani
clinical research dept., pasteur institute of iran, tehran, iran.

سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

محمد رضا شریف | mohammad reza sharif
department of pediatrics, kashan university of medical sciences, kashan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کاشان (Kashan university of medical sciences)

محمد بنی فضل | mohammad banifazl
iranian society for support of patients with infectious disease, tehran, iran.


علیرضا شریف | alireza sharif
department of infectious diseases, kashan university of medical sciences, kashan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کاشان (Kashan university of medical sciences)

علی اصغر فرازی | ali asghar farazi
tuberculosis and pediatric infectious research center, arak university of medical sciences, arak, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (Arak university of medical sciences)

علی اسلامی فر | ali eslamifar
clinical research dept., pasteur institute of iran, tehran, iran.

سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

فرشیده دیدگر | farshideh didgar
tuberculosis and pediatric infectious research center, arak university of medical sciences, arak, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اراک (Arak university of medical sciences)

آمیتیس رمضانی | amitis ramezani
clinical research dept., pasteur institute of iran, tehran, iran.

سازمان اصلی تایید شده: انستیتو پاستور ایران (Pasteur institute of iran)

نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/view/593
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