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Iranian Journal of Microbiology، جلد ۶، شماره ۱، صفحات ۱-۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Heterogeneity of Iranian clinical isolates of Mycobacterium fortuitum.
چکیده انگلیسی مقاله Background and Objectives: The increase of infections caused by nontuberculous mycobacteria (NTM) is receiving increasing attention worldwide. Mycobacterium fortuitum is encountered with increasing frequency in clinical laboratories of Iran. Materials and Methods: Sequence variation of 48 M. fortuitum clinical isolates, were investigated by sequence analysis of the 16S-23S Internal Transcribed Spacer. Results: Twelve different sequence types (sequevar) were identified by sequence analysis of ITS region. Seven previously described sequevar including MfoA, MfoB, MfoC, MfoD, MfoE, MfoF and MfoG identified. Five novel sequevar namely MfoH, MfoI, MfoJ, MfoK and MfoL that were distinctly different from the previously described sequevar were detected among different clinical strains of M. fortuitum , from Iran. Conclusion: This study showed that the ITS region possesses high discriminatory power between the clinical isolates up to the clonal level. The results also suggest the possibility of the existence of predominant clone of M. fortuitum in affected patients in Iran. The data also point to the conclusion that a large variety of M. fortuitum clone can produce disease although certain clones seem to be predominant.
کلیدواژه‌های انگلیسی مقاله ITS,Mycobacterium fortuitum,diversity
نویسندگان مقاله عبدالرزاق هاشمی شهرکی | abdolrazagh hashemi shahraki
infectious and tropical diseases research centre, ahvaz jundishapur university of medical sciences, ahvaz, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

پروین حیدریه | parvin heidarieh
department of bacteriology and immunology, school of medicine, alborz university of medical sciences, karaj, iran.


مریم بیرانوند | maryam biranvand
infectious and tropical diseases research centre, ahvaz jundishapur university of medical sciences, ahvaz, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

سعید ذاکر آباد | saeed zaker bostanabad
microbiology department, islamic azad university-parand branch, tehran, iran.

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

نسرین شیخی | nasrin sheikhi
masoud laboratory, tehran, iran.


محمد هاشم زاده | mohamad hashemzadeh
infectious and tropical diseases research centre, ahvaz jundishapur university of medical sciences, ahvaz, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

معصومه کرمی | masume karami
infectious and tropical diseases research centre, ahvaz jundishapur university of medical sciences, ahvaz, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

محمد مهدی فیض آبادی | mohammad mehdi feizabadi
department of microbiology, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/view/476
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