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Iranian Journal of Microbiology، جلد ۷، شماره ۶، صفحات ۳۳۳-۳۳۷
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عنوان انگلیسی The prevalence of Pneumocystis jirovecii among patients with different chronic pulmonary disorders in Ahvaz, Iran
چکیده انگلیسی مقاله Background and Objectives: Pneumocystis jirovecii pneumonia (PJP) is a chronic fungal infection that caused by P. ji- rovecii . Disease is more prevalent among the HIV-infected patients. The colonization of pneumocystis in human respiratory system is associated with the airway inflammation and obstruction. The current study was conducted to identify the preva- lence of P. jirovecii among the patients with chronic pulmonary disorders in Ahvaz, Iran. Materials and Methods: In the present study, 115 bronchoalveolar lavage (BAL) specimens were collected from patients. Samples were subjected to Nested-PCR with specific primers. The second PCR products were used for sequencing analysis. Results: Our findings demonstrated that 31(27.0%) of samples were positive for P. jirovecii . Nine patients (29%) have tuberculosis (TB) followed by, 1(3.2%) HIV positive and 21(67.7%) miscellaneous pulmonary disorders. Our results show that there was no significant differences between sex (male:female ratio, 17:14), TB, HIV and P. jirovecii in BAL samples (P>0.05). Conclusion: The current study is the first report from Ahvaz and it showed a relatively high frequency (27%) of P. jirovecii among patients with different pulmonary disorders. In addition Nested-PCR might be reliable technique for diagnosis of P. jirovecii , while the Grocott's methenamine silver (GMS) have a low sensitivity, which only two positive patients were identified.
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نویسندگان مقاله الهام aboualigalehdari | elham aboualigalehdari
department of medical mycology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

علی زارعی محمودآبادی | ali zarei mahmoudabadi
department of medical mycology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran and health research institute, infectious and tropical diseases research centre, ahvaz jundishapur university of medical sciences, ahvaz, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

مهناز فتاحی نیا | mahnaz fatahinia
department of medical mycology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

اسماعیل ایدنی | esmaeil idani
department of internal medicine, division of pulmonology, school of medicine, ahvaz jundishapur university of medical sciences, ahvaz, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (Ahvaz jundishapur university of medical sciences)

نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/view/127
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