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Iranian Journal of Basic Medical Sciences، جلد ۱۵، شماره ۲، صفحات ۷۸۳-۷۸۶
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Identification and Characterization of a High Vancomycin-Resistant Staphylococcus aureus Harboring VanA Gene Cluster Isolated from Diabetic Foot Ulcer |
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| چکیده انگلیسی مقاله |
Objective(s) Staphylococcus aureus is a common cause of human infection, and emergence of vancomycin-resistance S. aureus is a great concern for treatment of methicillin-resistant S. aureus,(MRSA) in recent years (MRSA). Here, we report the isolation of high-level VRSA. Materials and Methods S. aureus was isolated from foot ulcer of a diabetic woman in Tehran, Iran. Antibiotic susceptibility was determined according to CLSI guidelines. VanA gene cluster PCR was carried out and PCR amplicon of vanA was sequenced. Results S. aureus had high-level vancomycin-resistant (MIC 512 ≥ µg/ml). Patient's history revealed that VRSA isolate was acquired through community transmission. Only vanA, vanR and vanS genes were amplified in our isolate. Sequencing revealed that the vanA sequence had high similarity to the vanA sequence of Tn1546. Conclusion Although VRSA infection continues to be rare, isolation of community–acquired VRSA is a significant issue and it needs the efforts of public health authorities. |
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| کلیدواژه‌های انگلیسی مقاله |
Community-Acquired Infections, MRSA, Vancomycin Resistance |
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| نویسندگان مقاله |
آناهیتا دزفولیان | anahita dezfulian
research centre of gastroenterology and liver diseases rcgld in shahid beheshti university, tehran, iran
سازمان اصلی تایید شده: دانشگاه شهید بهشتی (Shahid beheshti university)
محمد مهدی اصلانی | mohammad mehdi aslani
department of microbiology, institute pasteur of iran, tehran, iran
مهوش اسکویی | mahvash oskoui
department of microbiology, institute pasteur of iran, tehran, iran
پریسا فرخ | parisa farrokh
department of microbiology, institute pasteur of iran, tehran, iran
معصومه عظیمی راد | masumeh azimirad
research centre of gastroenterology and liver diseases rcgld in shahid beheshti university, tehran, iran
سازمان اصلی تایید شده: دانشگاه شهید بهشتی (Shahid beheshti university)
حسین دبیری | hossein dabiri
research centre of gastroenterology and liver diseases rcgld in shahid beheshti university, tehran, iran
سازمان اصلی تایید شده: دانشگاه شهید بهشتی (Shahid beheshti university)
محمد تقی صالحیان | mohammad taghi salehian
research centre of gastroenterology and liver diseases rcgld in shahid beheshti university, tehran, iran
سازمان اصلی تایید شده: دانشگاه شهید بهشتی (Shahid beheshti university)
محمدرضا زالی | mohammad reza zali
research centre of gastroenterology and liver diseases rcgld in shahid beheshti university, tehran, iran
سازمان اصلی تایید شده: دانشگاه شهید بهشتی (Shahid beheshti university)
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| نشانی اینترنتی |
http://ijbms.mums.ac.ir/article_4853.html |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Short Communications |
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