این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Basic and Clinical Cancer Research، جلد ۳، شماره ۳&۴، صفحات ۲-۶
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Association of Hepatitis Virus on Acute and Chronic Myeloid Leukemias. A pilot Study
چکیده انگلیسی مقاله Background The induction of cancers incidence by exogenous agents, such as chemical, radiation and especially research on viruses is an interested area of active basic subjects and clinical investigation. Prominent researches sounds a high prevalence of HBV marker has been found in patients with leukemia as compared to the general population. Methods: Present  study was conducted from 1996 to 2010   among patients with chronic acute myeloid leukemia and corresponding with non malignant patients. In this investigation,  Cytochemical staining, immunophenotyping, cytogenetic /molecular cytogenetics, Elisa, enzyme immunoassay and Western blot, were the main subject of laboratory manipulation. Results: Hepatitis B virus was diagnosed in one non malignant control patient (%0.004) and four infected with leukemia patients (%3). The differences of leukemic patients revealed statistical significant when compared with non malignant patients ( P =0.0047). Conclusion: In this pilot study, the prevalence of HBV infection was higher in patients with leukemia than in patients as non malignant patients. Our findings are also important as they are among the first to suggest here a potentially significant influence of  HBV infection may plays a probably major role in the process of myeloid malignant development. However, the number of cases are not large enough to draw firm conclusion. Moreover, we suggest that this pilot study, issue warrants further investigation by large consortium project.
کلیدواژه‌های انگلیسی مقاله Leukemia,AML,CML,HBV,Association
نویسندگان مقاله ابوالفضل موفق | abolfazl movafagh
department of medical genetics, faculty of medicine, shahid beheshti university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

فرهاد شاویسی زاده | farhad shaveisi zadeh
department of pharmacology, faculty of medicine, shahid beheshti university of medical sciences, tehran, i.r. iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

علی حایری | ali haeri
department of pharmacology, faculty of medicine, shahid beheshti university of medical sciences, tehran, i.r. iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

مصطفی رضایی طاویرانی | mostafa rezaei tavirani
department of medical anatomy, faculty of medicine, shahid beheshti university of medical sciences, tehran, i.r. iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

محمد حسن حیدری | mohammad hassan heidari
department of medical epidemiology, shahid beheshti university of medical sciences, tehran, i.r. iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

علیرضا موسوی جراحی | alireza mousavi jarrahi


نشانی اینترنتی http://bccr.tums.ac.ir/index.php/bccrj/article/view/30
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/151/article-151-433660.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Articles
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