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Basic and Clinical Cancer Research، جلد ۴، شماره ۱&۲، صفحات ۱۶-۲۰
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عنوان انگلیسی Accuracy of Intraoperative Margin Investigation by Frozen-Section in Breast Conservative Surgery
چکیده انگلیسی مقاله Background: now the vast majority of breast tumors are treated using Breast conservation therapy (BCT) method, including lumpectomy and radiotherapy. This study aimed to evaluate the effects of intraoperative frozen section in patients undergoing breast conservation surgery. Methods: Totally 237 women who included in the category for breast conservative or oncoplastic surgery and post-operative radiotherapy (Early breast cancer Stage I,II and Stage IIIA after neoadjuvant chemotherapy and down staging) were enrolled in this prospective study from March 2009 to June 2011. Results: In frozen section, totally 88 margins (6.1%) in 60 patients (25%) was positive (1-5 positive margins/ patients) that all of these patients were re-excised. In precise pathologic view the margins in 7 patients (2.9%) was positive that comprised 4% of all margins, furthermore the results showed closed margin in 4 patients. false negative in our study occurred in 0.8% of patients and in 0.1% of margins (sensitivity 100% and specifity 99.2%). Conclusion: we designated intraoperative margin assessment by frozen section as an effective method in decreasing the rate of additional operations for margin control. Additionally, adequate margin width is accessible during same operation.
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نویسندگان مقاله ناهید نفیسی | nahid nafissi
cancer research center, shahid beheshti medical university, tehran, iran


مریم خیام زاده | maryam khayamzadeh
cancer research center, shahid beheshti medical university, tehran, iran


علیرضا صراف زاده | alireza sarafzadeh
department of pathology, shahid beheshti medical university, tehran, iran


محمد هاشمی | mohammad hashemi
department of anesthesiology, shahid beheshti medical university, tehran, iran


مسعود ثقفی نیا | masoud saghafinia
department of surgery, cancer institutet, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

معصومه نجفی | massoomeh najafi
breast cancer research center, acecr


آسیه الفت بخش | asieh olfatbakhsh
department of anesthesiology, shahid beheshti medical university, tehran, iran


حسن رفعتی | hasan rafati
cancer research center, shahid beheshti medical university, tehran, iran


محمد اسماعیل اکبری | mohammad esmaeil akbari


نشانی اینترنتی http://bccr.tums.ac.ir/index.php/bccrj/article/view/23
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/151/article-151-433656.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Articles
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