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Nanomedicine Journal، جلد ۴، شماره ۴، صفحات ۱۹۷-۲۰۷

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عنوان انگلیسی A review on electrospun nanofibers for oral drug delivery
چکیده انگلیسی مقاله Nowadays, polymer nanofibers have gained attention due to remarkable characteristics such as high porosity and large surface area to volume ratio. Among their fabrication methods, electrospinning technique has been attracted as a simple and reproducible approach. It is a versatile, simple and cost-effective technique for the production of continuous nanofibers with acceptable characteristics such as high porosity, high surface area to volume ratio, high loading capacity and encapsulation efficiency, delivery of multiple drugs, and enhancement of drug solubility. Due to these properties electrospun nanofibers have been extensively used for different biomedical applications including wound dressing, tissue engineering, enzyme immobilization, artificial organs, and drug delivery. Different synthetic and natural polymers have been successfully electrospun into ultrafine fibers. Using electrospun nanofibers as vehicles for oral drug delivery has been investigated in different release manners- fast, biphasic or sustained release. This article presents a review on application of electrospinning technique in oral drug delivery.    
کلیدواژه‌های انگلیسی مقاله Nanofiber, Electrospinning, Drug delivery, Polymer

نویسندگان مقاله عباس اخگری | abbas akhgari
targeted drug delivery research center, mashhad university of medical sciences, mashhad, iran|school of pharmacy, mashhad university of medical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

زهرا شکیب | zahra shakib
school of pharmacy, mashhad university of medical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

ستاره صنعتی | setareh sanati
school of pharmacy, mashhad university of medical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)


نشانی اینترنتی http://nmj.mums.ac.ir/article_9428.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Review Paper
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