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Journal of Arthropod-Borne Diseases، جلد ۱۱، شماره ۱، صفحات ۱۰۵-۱۱۵
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عنوان انگلیسی Repellency Effect of Essential Oils of Some Native Plants and Synthetic Repellents against Human Flea, Pulex irritans (Siphonaptera: Pulicidae)
چکیده انگلیسی مقاله Background: Fleas are important vectors of human and animal disease, and control measures for protection against their bites and flea-borne diseases are necessary. Methods : The essential oils (EOs) of four native medicinal plants, Ziziphora tenuiore , Myrtus communis , Achillea wilhelmsii and Mentha piperita were isolated by hydrodistillation technique and analyzed by GC-MC. The repellent activity of EOs and synthetic compounds, DEET and permethrin, were assayed on human subjects against field col­lected fleas. The effective doses of 50% and 90% of EOs and synthetic compounds were estimated by probit analysis of dose and response regression line. Results : Analysis of EOs revealed about 19 major components. All oils were found to be more repellent (ED 50 range= 208–955µg cm -2 ) than DEET and permethrin (ED 50 range= 27–182 x 10 3 µg cm -2 ). Thyme and myrtle oils showed high repellent activities and among the total detected terpenes, thymol (36.26%) and α- pinene (32.5%) were the major components of those oils respectively. Conclusion : Low repellent potency of DEET and permethrin against fleas might be related to flea olfactory system and further molecular and electrophysiological studies are required to conceive new ideas for the discovery and de­velopment of the next generation of repellents. Based on high repellent activity of thyme and myrtle essential oils against Pulex irritans further studies should be staged to develop their appropriate effective formulations. Likewise, field trials should be carried out to evaluate the operational feasibility and dermal toxicity over a long period.
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نویسندگان مقاله محمد باقر قوامی | mohammad bagher ghavami
department of medical entomology and vector control, faculty of medicine, zanjan university of medical sciences, zanjan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زنجان (Zanjan university of medical sciences)

فهیمه poorrastgoo | fahimeh poorrastgoo
zanjan health center, zanjan university of medical sciences, zanjan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زنجان (Zanjan university of medical sciences)

بهروز تقی لو | behrooz taghiloo
department of medical entomology and vector control, faculty of medicine, zanjan university of medical sciences, zanjan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زنجان (Zanjan university of medical sciences)

جمشید محمدی | jamshid mohammadi


نشانی اینترنتی http://jad.tums.ac.ir/index.php/jad/article/view/482
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/77/article-77-429964.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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