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Iranian Journal of Psychiatry، جلد ۱۲، شماره ۳، صفحات ۲۰۱-۲۰۵
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Relationship between BMI and depression, according to the rs16139NPY gene |
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| چکیده انگلیسی مقاله |
Objective: obesity and depression are likely to interact mutually which makes it unclear if obesity causes depression or it leads to obesity; and how the genotypes have a role in obesity and depression. Methods and Materials: This cross sectional study was conducted on a sample of 400 individuals from the participants in the third phase of the comprehensive Iranian Multicenter Osteoporosis Study (IMOS). Anthropometric measurements and depression were assessed. To investigate the NPY polymorphism, PCR-RFLP was used. Binary logistic regression model was employed to determine depression as the dependent factor and gene polymorphism Results: the frequency of NPY rs16139 was 6%. No significant association could be found between NPY genotypes and depression (p >0.05). Furthermore, the results suggest that those with central obesity seem an increased chance of developing depression (P=0.02). Conclusion: There is a significant relationship between obesity and depression and obesity is a possible cause of depression. Waist circumference and abdominal obesity as components of metabolic syndrome have the most important effects on depression. |
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| کلیدواژه‌های انگلیسی مقاله |
Depression, NPY polymorphism, , Obesity |
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| نویسندگان مقاله |
حمیده پیشوا | hamideh pishva
department of cellular-molecular nutrition, school of nutrition sciences and dietetics, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
عطیه دولتیان | atieh dolatian
department of cellular-molecular nutrition, school of nutrition sciences and dietetics, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
سید مسعود ارزاقی | seyed masoud arzaghi
elderly health research center, endocrinology and metabolism population sciences institute, tehran university of medical sciences, tehran, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
مصطفی قربانی | mostafa qorbani
school of medicine, community medicine department, alborz university of medical sciences, karaj, iran
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| نشانی اینترنتی |
http://ijps.tums.ac.ir/index.php/ijps/article/view/656 |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/64/article-64-413205.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Original Article(s) |
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