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Journal of Kerman University of Medical Sciences، جلد ۱۶، شماره ۳، صفحات ۲۲۵-۲۳۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Evaluation of DNA-content of Peritoneal Lavage Cells by Flow Cytometry in Patients with Gasteric Cancer
چکیده انگلیسی مقاله Background & Aims: Gastric cancer is the second common cancer in Iran and it has unfortunately no diagnostic signs in early stages. Considering the role of genetic and environmental factors in the development of gastric cancer, this study aimed at evaluating DNA-content of stomach cells in patients with gastric cancer in order to find a reliable index for prediction of disease prognosis and providing more exact therapeutic procedure. Methods: A total of 22 samples taken from patients with gastric cancer were evaluated. Peritoneal lavage cells were centrifuged and stained with DNA-staining kit. Then DNA-content was analyzed and compared with that in normal cells by employing flow cytometry and using modfit software. Results: In whole, 12 out of 22 samples were positive and DNA aneuploidy was present in 33.3%. SPF increase was observed in 22.2% of positive cases. Conclusion: SPF can be used as a reliable indicator in pathological staging of cancer and consequently in decision making for treatment.
کلیدواژه‌های انگلیسی مقاله DNA, Ploidy, Flow cytometry, Stomach neoplasms
نویسندگان مقاله علیرضا دیانی | a r
resident of general surgery, school of medicine, shahid beheshti university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

sh شاه قاسم پور | shah ghasempour
assistant professor of immunology, school of medicine, shahid beheshti university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

m مقیمی |
assistant professor of general surgery, school of medicine, shahid beheshti university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

f کمانی |
assistant professor of general surgery, school of medicine, shahid beheshti university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

s seyesgafori |
resident of obstetrics amp;amp; gynecology, school of medicine, iran, university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

h پیروی |
professor of general surgery, school of medicine, shahid beheshti university of medical sciences, tehran, iran..
سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

نشانی اینترنتی http://jkmu.kmu.ac.ir/article_17269_ff205467bdc763fd88cb5e2e7192b81c.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/93/article-93-405145.pdf
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زبان مقاله منتشر شده en
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