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Journal of Kerman University of Medical Sciences، جلد ۲۰، شماره ۳، صفحات ۲۹۲-۳۰۰
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عنوان انگلیسی The Effects of Opium Addiction through Different Administration Routes on Inflammatory and Coagulation Factors
چکیده انگلیسی مقاله Background & Aims: Based on an experimental trial, we tried to test the effects of opium addiction through different administration routes on inflammatory and Coagulation Factors. Methods: This study was performed on 30 adult male Syrian golden hamsters allocated to one of three groups: control group which received no opiate; the first study group received oral opiate; and another study group received inhaled opiate. After 4 weeks, all hamsters were anesthetized with diethyl ether and their blood samples were obtained from their hearts for laboratory assessment. Results: The blood level of hs-CRP was significantly higher in group used opium orally compared with the group used opium orally (P < 0.001); other markers were not different between the two experiments groups. The level of hs-CRP was higher in the two study groups than the controls. Blood hemocysteine levels following oral and inhaled opium use were comparable with the controls. Conclusion: Our study confirms the triggering role of opiate dependence through different administration routes on inflammatory process, especially through its oral usage.
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نویسندگان مقاله f merzaeipoor |
physiology research center, kerman university of medical sciences, kerman, iran assistant professor of cardiology, afzalipour school of medicine, kerman university of medical sciences, kerman, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

n ازدکی |
resident of cardiology, afzalipour school of medicine, kerman university of medical sciences, kerman, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

غلامعلی محمدی | gh a
associate professor of biochemistry, afzalipour school of medicine, kerman university of medical sciences, kerman, iran physiology research center, kerman university of medical sciences, kerman, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

e عباسی |
ph.d. candidate of biochemistry, hamedan university of medical sciences, hamedan, iran

نشانی اینترنتی http://jkmu.kmu.ac.ir/article_16449_dcf6dd51f871ad8074cd52c756a4a009.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/93/article-93-404956.pdf
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زبان مقاله منتشر شده en
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