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Journal of Kerman University of Medical Sciences، جلد ۲۴، شماره ۱، صفحات ۶۸-۷۷
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عنوان انگلیسی Association between Serum Uric Acid Level and Stenosis in Atherothrombotic Infarction
چکیده انگلیسی مقاله Background: Previous studies show that serum level of uric acid is significantly correlated with mortality and functional outcome in patients with ischemic stroke and according to some other studies, ischemic stroke is associated with stenosis of some stenoisis of somespecific brain vessels. The aim of this study was to investigate the frequency of hyperuricemia and its association with intra and extra cerebral vessels stenosis in patients with acute ischemic stroke. Method: In this cross-sectional study, 169 patients with acute atherothrombotic stroke were evaluated. Blood samples were collected in the first 24 hours after stroke for the assessment of uric acid. Doppler ultrasound was done in the first 5 days of stroke. To analyze data, t-test and logistic regression were used. Results: In this study, 22.4 % of patients had hyperuricemia. There was no significant statistical relationship between uric acid level and stenosis. Also, there was no significant statistical relationship between uric acid level and cerebrovascular risk factors. Mean serum uric acid level was 5.09±1/63 in patients with intracerebral vessels stenosis, 5.42±1.11in patients with extracerebral vessels stenosis and 6.18± 1.75 in patients with both intracerebral and extracerebral vessels stenosis. There was no significant statistical relationship between uric acid level and site of stenosis. Conclusion:Hyperuricemia is frequent in patients with acute ischemic stroke. The site of cerebral vessels stenosis is not associated with hyperuricemia.
کلیدواژه‌های انگلیسی مقاله Uric acid, Stroke, Arterial stenosis
نویسندگان مقاله محمد علی شفا | mohammad ali
associate professor of neurology, neurology research center, kerman university of medical sciences, kerman, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

رستم سیف الدینی |
assistant professor of neurology, neurology research center, kerman university of medical sciences, kerman, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

فرهاد ایرانمنش |
professor of neurology, stroke fellowship,neurology research center, kerman university of medical sciences, kerman, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

فاطمه سادات جعفری | sadat jafari
resident of neurology, neurology research center, kerman university of medical sciences, kerman, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

نشانی اینترنتی http://jkmu.kmu.ac.ir/article_42499_58ae56d064ed2534733b0218ed9a99aa.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/93/article-93-404745.pdf
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زبان مقاله منتشر شده en
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