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International Journal of Hematology-Oncology and Stem Cell Research، جلد ۷، شماره ۲، صفحات ۶-۱۰
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عنوان انگلیسی Association between Anemia and COPD in Iranian Population.
چکیده انگلیسی مقاله Chronic obstructive pulmonary disease (COPD) is one of the major causes of morbidity and mortality in adults. Anemia is known as comorbidity in many chronic diseases that can increase morbidity and mortality of COPD. Recent studies have shown that anemia may be more prevalent than expected in COPD patients and can increase disabilities of COPD. In this study we have evaluated the correlation between anemia and the severity of COPD in patients referred to teaching hospitals of the Tehran University of Medical Sciences (TUMS), Tehran, Iran.In this cross-sectional study the severity of COPD in 760 patients with dyspnea who referred to teaching hospitals of Tehran University of Medical Sciences and 96 stable COPD patients were categorize using a GOLD criteria from mild to moderate, severe and very severe. Anemia was determined as hemoglobin < 13 g/dL in men and < 12 g/dL in women, respectively. Demographic characteristics, spirometry parameters and laboratory findings were compared between anemic and non-anemic groups using Student t-test and regression tests (SPSS v.18 software).The Mean age of patients was 65 ± 13.07 years (59.4% male). Overall prevalence of anemia was 27% and there was no correlation between severity of COPD and anemia. Anemic patients were significantly older than non-anemic patients (71.1 ± 8.5 years vs. 65.4± 12.8 years; p = 0.030). RBC count of anemic patients were significantly lower than non-anemic group (4.3 ± 0.5 vs. 5.02± 0.8 ×106/µL; p < 0.001). Erythropoietin levels in anemic group was significantly higher than non-anemic group (16.33±2.43 vs. 10.22 ± 2.67 mu/ml; p < 0.001) and there was a significant inverse correlation of hemoglobin vs erythropoietin (r= -0.8).There was a high prevalence of anemia in COPD patients. Anemia can increase disabilities of COPD. Thus, treatment of anemia may improve quality of life in these patients. Further comprehensive studies are needed for determination of exact prevalence of anemia and its physiologic effects in COPD.
کلیدواژه‌های انگلیسی مقاله Anemia,COPD
نویسندگان مقاله روشنک هاشمی نسب zavarreh | roshanak hasheminasab zavarreh
pulmonary diseases research center, rasoul-e-akram hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

محمد مهدی زحمتکش | mohammad mehdi zahmatkesh
pulmonary diseases research center, rasoul-e-akram hospital, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

مسعود وکیلی | masood vakili
hematology-oncology department of rasoul-e akram hospital, iran university of medical sciences,tehran,iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

علی شهریاری احمدی | ali shahriari ahmadi
hematology-oncology department of rasoul-e akram hospital, iran university of medical sciences,tehran,iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

محمد علی زحل | mohammad ali zohal
associate professor of internal medicine, pulmonologist, qazvin university of medical since, qazvin, iran.


محسن عربی | mohsen arabi
hematology-oncology department of rasoul-e akram hospital, iran university of medical sciences,tehran,iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

علیرضا محمودیان | alireza mahmoudian
microbiology department of oroumieh university, oroumieh, iran.


عباس gheisuri | abbas gheisuri
hematology-oncology department of rasoul-e akram hospital, iran university of medical sciences,tehran,iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

عبدالحامد کیان | abdolhamed kian
hematology-oncology department of rasoul-e akram hospital, iran university of medical sciences,tehran,iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

علی فهیمی | ali fahimi
hematology-oncology department of rasoul-e akram hospital, iran university of medical sciences,tehran,iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

نشانی اینترنتی http://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/458
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