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مجله پزشکی ارومیه، جلد ۳۶، شماره ۲، صفحات ۱۴۳-۱۵۱
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عنوان انگلیسی Evaluation of Methadone Poisoning, Clinical Manifestations, and Laboratory Findings in Hospitalized Children at Shahid Motahari Hospital, Urmia, During 2019–2024
چکیده انگلیسی مقاله Background Poisoning is one of the common causes of visits to emergency departments. Opioids and methadone are among the leading causes of unintentional poisoning, particularly in children, leading to a high burden of pediatric emergency admissions. This study was conducted to evaluate methadone poisoning, clinical manifestations, and laboratory findings.
Methods This descriptive cross-sectional study was performed using a census approach on the medical records of 107 children hospitalized due to methadone poisoning at Shahid Motahari Educational and Medical Center, Urmia, between 2019 and 2024. Data were collected using a checklist including demographic characteristics, clinical symptoms, and laboratory findings. Data analysis was conducted using SPSS version 26 through descriptive statistics and frequency distribution (absolute and percentage).
Results The mean age of the patients was 41 ± 52 months, with 62.6% falling within the age range of 13–59 months. A total of 59.8% were presented within less than 12 hours, 57% were boys, 81.3% of poisonings were accidental, and 64.5% were poisoned with methadone syrup. Clinical symptoms included miosis in 72.9%, decreased level of consciousness in 78.5%, seizures in 2.8%, respiratory arrest in 10.3%, intubation in 8.4%, and death in one case (0.9%). Laboratory findings showed metabolic acidosis in 35.5%, anemia in 59.8%, hyperglycemia in 43%, and positive urinary methadone in 71%. Naloxone was administered in 95.7% of patients.
Conclusion Parental education on preventing accidental methadone ingestion, timely referral to medical centers in case of poisoning symptoms, and training provided by addiction treatment centers on safe storage of methadone are effective strategies in reducing methadone poisoning among children.
کلیدواژه‌های انگلیسی مقاله Child, Clinical manifestations, Laboratory findings, Methadone, Poisoning
نویسندگان مقاله | Neda Pashaei yingje
Clinical Research Development Unit, Shahid Motahari Educational and Medical Center, Urmia University of Medical Sciences, Urmia, Iran


| Mir Reza Ghaemi
Department of Pediatrics, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran


| Mahsa Salehzadeh Nobari
Clinical Research Development Unit, Shahid Motahari Educational and Medical Center, Urmia University of Medical Sciences, Urmia, Iran


| Mahnaz Mohamadpouri
Clinical Research Development Unit, Shahid Motahari Educational and Medical Center, Urmia University of Medical Sciences, Urmia, Iran


| sima ghanipourbadelbuu
Department of Nursing and Midwifery, Urmia Branch, Islamic Azad University, Urmia, Iran
نشانی اینترنتی http://umj.umsu.ac.ir/browse.php?a_code=A-10-4241-3&slc_lang=en&sid=1
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زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده کودکان (عمومی)
نوع مقاله منتشر شده پژوهشی(توصیفی- تحلیلی)
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