Iranian Journal of Microbiology، جلد ۱۷، شماره ۴، صفحات ۶۰۶-۶۱۲

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عنوان انگلیسی Implementation of hazard analysis and critical control points (HACCP) for microbial safety of enteral feeding solutions at Imam Khomeini Hospital, Urmia, Iran
چکیده انگلیسی مقاله Background and Objectives: Enteral feeding solutions (gavage) play a vital role in supporting ICU patients who cannot eat by mouth. However, their preparation is vulnerable to microbial contamination, posing serious health risks. This study aimed to assess and improve the microbial safety of enteral feeding solutions prepared at Imam Khomeini Hospital in Urmia, Iran. Materials and Methods: A three-phase intervention was conducted involving microbial and PCR analyses, source identification, and corrective measures. Initial testing revealed high contamination levels: coliform bacteria (>5×10³ CFU/mL), fungi (>3×10³ CFU/mL), and total mesophilic bacteria (>10⁴ CFU/mL). PCR analysis confirmed the absence of Escherichia coli and Klebsiella spp. Corrective actions—such as installing UV lighting, implementing enhanced cleaning protocols, and replacing the mixing device—were introduced. Results: Post-intervention analyses showed complete elimination of detectable microbial contamination in the gavage solutions. Conclusion: This study demonstrates that implementing a HACCP-based approach can effectively eliminate microbial contamination in enteral feeding solutions. The findings support the development of national guidelines and highlight the importance of standardized safety practices to improve patient care in hospital settings.
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نویسندگان مقاله | Mohammad Yousefi
Food and Beverages Safety Research Center, Urmia University of Medical Sciences, Urmia, Iran


| Kave Koorehpaz
Department of Theriogenology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran


| Morteza Bagheri
Cellular and Molecular Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran


| Yaghob Sharifi
Department of Microbiology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran


| Amir Rahimirad
Food and Drug Administration, Urmia University of Medical Sciences, Urmia, Iran


| Yousef Roosta
Department of Internal Medicine, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran



نشانی اینترنتی https://ijm.tums.ac.ir/index.php/ijm/article/view/5336
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