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Journal of Dentistry, Shiraz University of Medical Sciences، جلد ۲۶، شماره ۳، صفحات ۲۸۴-۲۸۷
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عنوان انگلیسی Mandibular Metastatic Breast Cancer: A Rare Case Report with Diagnostic Challenge
چکیده انگلیسی مقاله Jawbone metastatic lesions are a diagnostic challenge because of their rarity and variable clinical, radiographic, and histopathologic characteristics. This paper presents a 57-year-old female with a chief complaint of lower face swelling. Cone beam computed tomography (CBCT) showed a multilocular radiolucency with right angle septa in the left mandibular area with cortical destruction. She had a history of right breast cancer about six years ago. Histopathologic examination revealed sheets of malignant small round cells. Immunohistochemistry (IHC) was only positive for cytokeratin (CK) and GATA3. CA15-3 tumor marker was higher than the normal range. Based on the aforementioned data, the diagnosis of metastatic breast carcinoma was performed. The whole-body and computed tomography (CT) scan showed just involvement in the left mandibular area. The radiographic appearance of metastatic lesions might be misleading, and microscopic sections might be poorly differentiated, therefore, a precise past medical history, IHC staining, and tumor markersre valuable issues in diagnosing oral cavity metastasis.
کلیدواژه‌های انگلیسی مقاله Metastasis,Breast cancer,Mandible,oral cavity
نویسندگان مقاله Mohammad Mehdizadeh |
Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Qom University of Medical Sciences, Qom, Iran.

Ali Lotfi |
Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Saede Atarbashi-Moghadam |
Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Parsa Eftekhari-Moghadam |
Undergraduate Student, Research Committee, School of Dentistry, Shahid Beheshti, University of Medical Sciences, Tehran, Iran.

نشانی اینترنتی https://dentjods.sums.ac.ir/article_50650_64358ddf6555077c332db4b2fd2b1e11.pdf
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