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Journal of Dentistry, Shiraz University of Medical Sciences، جلد ۲۶، شماره ۳، صفحات ۲۳۳-۲۴۰
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عنوان انگلیسی The Effects of Nanohydroxyapatite with and without Low-Power Laser and Cold Atmospheric Plasma on Enamel Remineralization: in vitro Study
چکیده انگلیسی مقاله Background: Remineralizing early enamel lesions in primary dentition remain a significant challenge in dentistry, requiring innovative approaches to enhance enamel repair. Purpose: This study aimed to evaluate the efficacy of a commercially available nanohydroxyapatite paste (Nano P), alone and in combination with air dielectric barrier discharge cold atmospheric plasma (CAP) and a 940-nm diode laser, on enamel remineralization. Materials and Method: In this in vitro study, 105 intact anterior primary teeth were randomly assigned into one control and six experimental groups: (I) control, (II) Fluoride varnish, (III) Nano P, (IV) Nano P + dye + laser, (V) Nano P + laser, (VI) CAP, and (VII) Nano P + CAP. Caries-like lesions were induced by demineralization. Microhardness was evaluated before and after demineralization and 4 weeks post-remineralization with pH cycling. Data analysis was conducted using one-way ANOVA (α=.05) and Tamhane’s Post-Hoc test, with effect sizes determined by Cohen’s d test and Hedges' g correction. The percentage of recovery of the enamel microhardness was calculated Results: Initial and secondary microhardness were similar across groups (p Value >.05). Post-remineralization, significant differences were observed (p< 0.05), with the highest microhardness in the Nano P+ laser group, followed by Nano P+ dye+ laser, Nano P+ CAP, Nano P, fluoride varnish, CAP, and the control. Pairwise comparisons showed significant differences between all pairs except Nano P+ laser and Nano P+ dye + laser (p= 0.7, Effect size=0.4). Conclusion: Nano P combined with a laser, followed by Nano P with plasma, and Nano P alone significantly increased microhardness more than fluoride or plasma, suggesting these combinations as effective alternatives for enamel remineralization in primary teeth.
کلیدواژه‌های انگلیسی مقاله cold plasma,Diode Laser,Fluorides,Hydroxyapatites,Hardness Test
نویسندگان مقاله Pegah Bakhtiary |
Dept. of Pediatric Dentistry, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.

Matine Gharavi |
Postgraduate Student, Dept. of Pediatric Dentistry, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.

Hooman Ebrahimi |
Oral Medicine Specialist, Fellowship in Orofacial Pain, Fellowship in Laser in Dentistry, Researcher, Oral Medicine Department, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.

Katayoun Salem |
Dept. of Pediatric Dentistry, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. Second Affiliation University of Applied Science and Technology, EbneSina Center, Tehran, Iran.

نشانی اینترنتی https://dentjods.sums.ac.ir/article_50611_37408bb0e9fff012044c7281e73253e1.pdf
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