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International Journal of Radiation Research، جلد ۲۳، شماره ۲، صفحات ۲۹۷-۳۰۵
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Effects of laparoscopic ultrasound-guided microwave ablation in combination with surgical resection on liver function and immune function in primary liver cancer patients |
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| چکیده انگلیسی مقاله |
Background: To investigate the effects of laparoscopic ultrasound (LUS)-guided microwave ablation (MWA) combined with surgical resection on liver function and immune function of primary liver cancer (PLC) patients. Materials and Methods: Clinical data of 100 patients with PLC after surgery in our hospital from January 2021 to December 2023 were retrospectively analyzed, and divided into laparoscopic hepatectomy (LH group) and laparoscopic ultrasound-guided microwave ablation combined with laparoscopic hepatectomy (LMWA+LH group). Clinical indicators, clinical efficacy, liver function, tumor markers, immune function, incidence of complications, postoperative overall survival rate along with tumor free survival rate between groups were compared. Results: Compared with the LH group, the intraoperative blood loss and postoperative hospital stay was decreased in the LMWA+LH group (P<0.05). Total effective rate of the LMWA+LH group was 90.00%, higher than the 70.00% in LH group (P<0.05). After therapy, reduction in aspartate alanine aminotransferase (ALT), aminotransferase (AST), total bilirubin (TBIL), and the elevation in albumin (ALB) in the LMWA+LH group were more obvious (P<0.05). The LMWA+LH group showed more obvious elevation in CD4+ and CD4+/CD8+ levels and reduction in CD8+ level relative to the LH group (P<0.05). The complication incidence showed no statistical difference between groups (P>0.05). Postoperative survival and tumor free survival rates in the LMWA+LH group were higher than LH group (P<0.05). Conclusion: Laparoscopic ultrasound-guided microwave ablation combined with surgical resection promotes the postoperative recovery, improves liver function and immune function and improves patient survival rate, which might provide guidance for clinical practice. |
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| کلیدواژه‌های انگلیسی مقاله |
IMRT, Primary liver cancer, ultrasonography, microwave ablation, hepatectomy, liver function, immune function. |
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| نویسندگان مقاله |
| L. Zhu
Department of Ultrasonic Medicine, Yichun City People's Hospital, Yichun 336000, Jiangxi, China
| L. Chen
Department of Ultrasonic Medicine, The First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi, China
| N. Tao
Department of Ultrasonic Medicine, Yichun City People's Hospital, Yichun 336000, Jiangxi, China
| N. Tao
Department of Ultrasonic Medicine, Yichun City People's Hospital, Yichun 336000, Jiangxi, China
| J. Pan
Department of Ultrasonic Medicine, Yichun City People's Hospital, Yichun 336000, Jiangxi, China
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| نشانی اینترنتی |
http://ijrr.com/browse.php?a_code=A-10-1-1328&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Radiation Biology |
| نوع مقاله منتشر شده |
تحقیق بدیع |
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