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Iranian Journal of Psychiatry، جلد ۵، شماره ۴، صفحات ۱۶۴-۱۶۶
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عنوان انگلیسی Trazodone in methandone induced erectile dysfunction.
چکیده انگلیسی مقاله Based on findings of previous studies, those men on Methadone Maintenance Therapy (MMT) have a high prevalence of Erectile Dysfunction(ED), related to hypogonadism and depression. We conducted this study to evaluate the efficacy of Trazodone (an antidepressant which can improve sexual function) on this sexual dysfunction.A structured interview was administered by the clinical staff. The interview contained questions about the subjects' socio-demographic characteristics, their drug use and sexual behavior. In addition to the socio-demographic survey, erectile function was assessed using erectile dysfunction (ED) intensity scale. Of the 157 subjects, 95 suffered from ED. The subjects were informed about the study. Then, seventy five patients voluntarily received 50mg of Trazodone for four days, and the dosage was increased to100 mg and maintained for 6 weeks. Fifty five patients who completed the treatment course were assessed by ED questionnaire again at the end of study. Statistical analysis was performed using Stata 8 software.The prevalence of ED was 60.5% in our sample. The mean erectile dysfunction (ED) intensity scale was 12.21, and 16.78 before and after the treatment course respectively. (P 0.05); but it had a significant relation with duration of Methadone therapy and Methadone daily dosage. (p< 0.05)Trazodone may be effective in the treatment of methadone induced ED. Further studies with control groups and greater sample sizes are warranted.
کلیدواژه‌های انگلیسی مقاله Erectile dysfunction,Methadone,Trazodone
نویسندگان مقاله فایزه تاتاری | faezeh tatari
behavioral sciences research center, kermanshah university of medical sciences, kermanshah, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

وحید فرنیا | vahid farnia
behavioral sciences research center, kermanshah university of medical sciences, kermanshah, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

رضا فقیه نصیری | reza faghih nasiri
behavioral sciences research center, kermanshah university of medical sciences, kermanshah, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

فرید نجفی | farid najafi
department of statistics and epidemiology, kermanshah university of medical sciences, kermanshah, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمانشاه (Kermanshah university of medical sciences)

نشانی اینترنتی http://ijps.tums.ac.ir/index.php/ijps/article/view/344
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