|
|
Iranian Journal of Radiology، جلد ۱۲، شماره ۳، صفحات ۰-۰
|
|
|
| عنوان فارسی |
Non Secretory Multiple Myeloma With Extensive Extramedullary Plasmacytoma: A Diagnostic Dilemma |
|
| چکیده فارسی مقاله |
Multiple myeloma (MM) is characterized by progressive proliferation of malignant plasma cells, usually initiating in the bone marrow. MM can affect any organ; a total of 7 - 18% of patients with MM demonstrate extramedullary involvement at diagnosis. Non-secretory multiple myeloma (NSMM) is a rare variant that accounts for 1 - 5% of all cases of multiple myeloma. The disease is characterized by the absence of monoclonal gammopathy in serum and urine electrophoresis. Our case report highlights the diagnostic challenge of a case of NSMM with extensive extramedullary involvement in a young female patient who initially presented with right shoulder pain and bilateral breasts lumps. Skeletal survey showed multiple lytic bony lesions. The initial diagnosis was primary breast carcinoma with osseous metastases. No monoclonal gammopathy was found in the serum or urine electrophoresis. Bone marrow and breast biopsies revealed marked plasmacytosis. The diagnosis was delayed for a month in view of the lack of clinical suspicion of multiple myeloma in a young patient and scant biochemical expression of non-secretory type of multiple myeloma. |
|
| کلیدواژه‌های فارسی مقاله |
Multiple Myeloma،Plasmacytoma |
|
| عنوان انگلیسی |
Non Secretory Multiple Myeloma With Extensive Extramedullary Plasmacytoma: A Diagnostic Dilemma |
|
| چکیده انگلیسی مقاله |
Multiple myeloma (MM) is characterized by progressive proliferation of malignant plasma cells, usually initiating in the bone marrow. MM can affect any organ; a total of 7 - 18% of patients with MM demonstrate extramedullary involvement at diagnosis. Non-secretory multiple myeloma (NSMM) is a rare variant that accounts for 1 - 5% of all cases of multiple myeloma. The disease is characterized by the absence of monoclonal gammopathy in serum and urine electrophoresis. Our case report highlights the diagnostic challenge of a case of NSMM with extensive extramedullary involvement in a young female patient who initially presented with right shoulder pain and bilateral breasts lumps. Skeletal survey showed multiple lytic bony lesions. The initial diagnosis was primary breast carcinoma with osseous metastases. No monoclonal gammopathy was found in the serum or urine electrophoresis. Bone marrow and breast biopsies revealed marked plasmacytosis. The diagnosis was delayed for a month in view of the lack of clinical suspicion of multiple myeloma in a young patient and scant biochemical expression of non-secretory type of multiple myeloma. |
|
| کلیدواژه‌های انگلیسی مقاله |
Multiple Myeloma,Plasmacytoma |
|
| نویسندگان مقاله |
soo fin low | soo fin low
department of radiology, malaysia medical center, university kebangsaan, kuala lumpur, malaysia; department of radiology, malaysia medical center, university kebangsaan, kuala lumpur, malaysia. tel 6-0391456194, fax 6-0391456682
نور حنانی محمد tap | nor hanani mohd tap
department of radiology, malaysia medical center, university kebangsaan, kuala lumpur, malaysia
thean yean kew | thean yean kew
department of radiology, malaysia medical center, university kebangsaan, kuala lumpur, malaysia
چای soon ngiu | chai soon ngiu
department of medicine, malaysia medical center, university kebangsaan, kuala lumpur, malaysia
radhika sridharan | radhika sridharan
department of radiology, malaysia medical center, university kebangsaan, kuala lumpur, malaysia
|
|
| نشانی اینترنتی |
http://www.Iranjradiol.com/index.php?page=article&article_id=11760 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
10.5812/iranjradiol.11760v2 |
| زبان مقاله منتشر شده |
fa |
| موضوعات مقاله منتشر شده |
|
| نوع مقاله منتشر شده |
case-report |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|