|
|
Medical Laboratory Journal، جلد ۱۰، شماره ۵، صفحات ۳۳-۳۹
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Impact of Aerobic Exercise on Restoration of Soleus and Gastrocnemius Muscles Microcirculations in Wistar Rats with Chronic Heart Failure |
|
| چکیده انگلیسی مقاله |
ABSTRACT Background and Objective: Scientific evidence reveals that the density of skeletal muscle microcirculations decreases in the patients with chronic heart failure. Therefore, this study aimed to determine the impact of submaximal aerobic exercise training on restoration of fast/slow-twitch muscle fibers microcirculation in rats with myocardial infarction. Methods: In this experimental study, 30 male infarcted Wistar rats were randomly divided into three groups of sham (N=10), control (N=10) and exercise (N=10), four weeks after surgery (blockage of anterior descending artery). Daily aerobic exercise included running on a treadmill for 10 weeks (5 times a week) at a speed of 17 m/min within 10 to 50 minutes. The animals were anesthetized and then sacrificed with chloroform, 48 hours after the last training session. The microcirculation density of soleus (SOL) and gastrocnemius (Gw) muscles was evaluated by immunohistochemistry assay. Results: Capillary density and capillary to SOL muscle fiber ratio significantly increased in response to exercise training. However, capillary density, capillary to Gw muscle fiber ratio and Gw muscle arteriolar density of Wistar rats with chronic heart failure were not significantly affected by the exercise program. Moreover, arteriolar density of Gw muscle increased significantly after the exercise program. Conclusion: The ten-week aerobic exercise might non-uniformly improve the SOL and Gw muscles microcirculation in rats with chronic heart failure by increasing capillary density and capillary to fiber ratio in the SOL muscle and increasing the arteriolar density of the Gw muscle. Keywords: Heart Failure, Angiogenesis, Exercise. |
|
| کلیدواژه‌های انگلیسی مقاله |
Heart Failure, Angiogenesis, Exercise. |
|
| نویسندگان مقاله |
فرزاد ناظم | farzad nazem
department of sport physiology, faculty of physical education and sport sciences, bu-ali sina university, hamedan, iran
سازمان اصلی تایید شده: دانشگاه بوعلی سینا (Bu ali sina university)
ملیحه اردکانی | malihe ardakani
department of sport physiology, faculty of physical education and sport sciences, bu-ali sina university, hamedan, iran
سازمان اصلی تایید شده: دانشگاه بوعلی سینا (Bu ali sina university)
محمدرضا غلامی | mohammad reza gholami
department of anatomy, razi herbal medicine research center, lorestan university of medical sciences, khorramabad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی لرستان (Lorestan university of medical sciences)
کمال رنجبر | kamal ranjbar
department of physical education and sport sciences, bandar abbas branch, islamic azad university, bandar abbas, iran
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)
افشین نظری | afshin nazari
department of physiology, razi herbal medicine research center, lorestan university of medical sciences, khoramabad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی لرستان (Lorestan university of medical sciences)
|
|
| نشانی اینترنتی |
http://goums.ac.ir/mljgoums/browse.php?a_code=A-10-1-421&slc_lang=fa&sid=fa |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/168/article-168-326928.pdf |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
تخصصی |
| نوع مقاله منتشر شده |
تحقیقی |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|