این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Nanomedicine Journal، جلد ۱۱، شماره ۴، صفحات ۴۵۰-۴۵۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Antibacterial activity of green synthesized silver nanoparticles using Pistacia hull against multidrug-resistant clinical isolates
چکیده انگلیسی مقاله Objective(s): Silver nanoparticles (AgNPs) can be considered as the new antibacterial agents. The antibacterial effects of synthesized AgNPs from Iranian pistachio hulls on several antibiotic-resistant bacteria were assessed in this study. Materials and Methods: In an experimental study, AgNPs were synthesized by reducing Ag+ ions using pistachio hulls. Several methods characterized the qualities of AgNPs. Antibacterial activities of the AgNPs against six gram-positive and gram-negative standard bacteria and 30 multidrug-resistant (MDR) clinical isolates were investigated by well diffusion, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) methods. Results: The aqueous extract of pistachio hulls had an acceptable potential to synthesize AgNPs, and the formed nanoparticles displayed suitable size and acceptable stability in solutions. Antibacterial activities of the AgNPs were detected against two standard strains, Escherichia coli, and Staphylococcus aureus, with growth inhibition zones of 13 and 11 mm, respectively. MIC were 10 mg/ml for E. coli and 20 mg/ml for S. aureus. MBC for both bacteria was the same as MIC. MIC and MBC AgNPs against 15 methicillin-resistant S. aureus (MRSA) isolates ranged from 40 to 10 mg/ml. In extended-spectrum beta-lactamase (ESBL) E. coli isolates, 11 and 3 isolates have MIC equal to 20 and 10 mg/ml, respectively. Three ESBL E. coli isolates had 10, 5 and 2.5 mg/ml MBC; in other isolates, MBC and MIC were the same. Conclusion: The green synthesis of AgNPs using pistachio hull can replace common chemical and physical methods. AgNPs displayed antibacterial activities, and they could replace some antibiotics. 
کلیدواژه‌های انگلیسی مقاله Anti-Bacterial Agents, Drug resistance, Green chemistry technology, Nanoparticles, Pistacia
نویسندگان مقاله | Zary Nokhodian
Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran


| Mohammad Mousavi-Khattat
Department of Biotechnology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran


| Shima Gharibi
Core Research Facilities, Isfahan University of Medical Sciences, Isfahan, Iran


| Soodabeh Rostami
Nosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, Iran


| Parisa Zeraati
Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran


| Mehdi Rahimmalek
Department of Horticulture, College of Agriculture, Isfahan University of Technology, Isfahan, Iran


| Antoni Szumny
Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, Wroclaw, Poland
نشانی اینترنتی https://nmj.mums.ac.ir/article_24604.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده مقاله پژوهشی
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات