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Journal of Dentistry, Shiraz University of Medical Sciences، جلد ۱۸، شماره ۱، صفحات ۴۳-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Immunohistochemical Comparison of the Expression of CD34 and CD105 in Odontogenic Keratocyst and Dentigerous Cyst
چکیده انگلیسی مقاله Statement of the Problem: Odontogenic keratocyst (OKC) is a developmental odontogenic cyst with specific histopathological features, high recurrence rate, and aggressive clinical behavior. Angiogenesis might be considered as an important factor for the growth, expansion, and distribution of this lesion. Purpose: The aim of the present study was to determine the mean vascular densities (MVD) of OKCs and dentigerous cysts to evaluate their relationship with the biologic behavior of these lesions. Materials and Method: In this cross-sectional analytical study, angiogenesis was assessed in OKC and dentigerous cyst by measuring the MVD. Immunohistochemistry was carried out using CD34 and CD105. The results were analyzed with independent samples t-test. The data were analyzed, setting p value at 0.05. Results: The MVDs with the use of CD34 and CD105 markers were significantly higher in OKC compared to dentigerous cyst ( p < 0.05). In addition, MVDs obtained by CD105 in dentigerous cysts and OKC were significantly less than those based on CD34 ( p < 0.05). Conclusion: Based on the results of the present study, it can be suggested that angiogenesis might be one of the possible mechanisms involved in higher aggressive biologic behavior and greater recurrence rate of OKC compared to dentigerous cysts. Keywords ● CD105 ● CD34 ● Dentigerous cyst ● Immunohistochemistry ● Odontogenic keratocyst
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله شکوفه جمشیدی | shokoofeh jamshidi
dental research center, dept. of oral and maxillofacial pathology, school of dentistry, hamadan university of medical sciences, hamadan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

معصومه زرگران | massoumeh zargaran
dental research center, dept. of oral and maxillofacial pathology, school of dentistry, hamadan university of medical sciences, hamadan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

قدرت اله روشنایی | ghodratollah roshanaei
dept. of biostatistics, hamadan university of medical sciences amp;amp; health services, hamadan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی همدان (Hamadan university of medical sciences)

فاطمه حدادی | fatemeh hadadi
dept. of oral and maxillofacial pathology, school of dentistry, shiraz university of medical sciences, shiraz, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

علی دهقانی ناژوانی | ali dehghani nazhvani
dept. of oral and maxillofacial pathology, school of dentistry, shiraz university of medical sciences, shiraz, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

نشانی اینترنتی http://dentjods.sums.ac.ir/index.php/JDSUMS/article/view/1352
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/331/article-331-323399.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Article
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