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Middle East Journal of Digestive Diseases، جلد ۱۶، شماره ۲، صفحات ۱۱۴-۱۱۸
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عنوان انگلیسی Efficacy of Oral Gabapentin and Acetaminophen for Postoperative Analgesia in Anorectal Surgery: A Fuzzy Logic Evaluation
چکیده انگلیسی مقاله Background: The present study attempted to evaluate the effect of oral gabapentin and acetaminophen for postoperative analgesia in anorectal surgery.   Methods: This double-blind clinical trial was carried out on 144 patients who were candidates for anorectal surgery. The patients were randomly assigned into three groups of control, acetaminophen 500 mg, and gabapentin 300 mg for two hours before the surgery. Data on pain severity based on the visual analog scale (VAS) were evaluated and analyzed.   Results: The results of the current study indicated that in patients taking acetaminophen and gabapentin tablets before surgery, the amount of postoperative pain decreased, and the amount of decrease in postoperative pain in the patients who received acetaminophen and gabapentin tablets compared with the placebo group was significant (P<0.001). Also, an evaluation was done using a proposed fuzzy logic model.   Conclusion: Taking acetaminophen and gabapentin tablets one hour before the operation causes a significant reduction in postoperative pain in patients who are candidates for anorectal surgery. The results are promising and encourage one to pay attention to more studies with the goal of possibly using them as a decision-support model in the future.  
کلیدواژه‌های انگلیسی مقاله Anorectal pain, Acetaminophen, Gabapentin, Anorectal surgery, Fuzzy logic
نویسندگان مقاله | Seyed Jalal Ishagh hosseini
Department of Electrical and Computer Engineering, Naein Branch, Islamic Azad University, Naein, Iran.


| Pouya Derakhshan Barjoei
Department of General Surgery, Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran.


| Mojdeh Bahadorzadeh
Department of General Surgery, Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran.


| Amin Seifaddini
Department of Social and Family Medicine, Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran.


| Mostafa Vahedian


نشانی اینترنتی http://mejdd.org/index.php/mejdd/article/view/2902
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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