|
|
Nanomedicine Journal، جلد ۴، شماره ۱، صفحات ۱-۷
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Recent advances in nanoformulations for co-delivery of curcumin and chemotherapeutic drugs |
|
| چکیده انگلیسی مقاله |
The application of chemotherapy in cancer treatment has been limited due to cause side effects such as toxicity against normal cells and drug resistance. In recent years, numerous studies have been focused on using natural products with chemotherapeutic drugs to enhance therapeutic efficiency and reduce cytotoxicity. On the other hand, encapsulation of drugs into nanoparticles (NPs) can improve solubility of hydrophobic drug; circulation time in blood and the residence at the pathological site by enhance permeation and retention (EPR) effect. It has been shown that curcumin (CUR) has wide range of pharmacological activities against many diseases such as cancer. CUR has been demonstrated to be a potent chemosensitizer that can induce additive or synergistic effects with chemotherapeutic drugs against different cancer cell lines. Recently, various types of nanocarriers have been investigated for CUR. In this review, different co-formulations containing Cur and chemotherapeutic drugs used in cancer therapy are discussed with emphasis on their pharmaceutical properties. |
|
| کلیدواژه‌های انگلیسی مقاله |
Cancer, Curcumine, Co-delivery, Nanoformulation |
|
| نویسندگان مقاله |
مریم هاشمی | maryam hashemi
nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
محبوبه ابراهیمیان | mahboubeh ebrahimian
division of biotechnology, faculty of veterinary medicine, ferdowsi university of mashhad, mashhad, iran
سازمان اصلی تایید شده: دانشگاه فردوسی (Ferdowsi university)
|
|
| نشانی اینترنتی |
http://nmj.mums.ac.ir/article_8046.html |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/295/article-295-313990.pdf |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
|
| نوع مقاله منتشر شده |
3 |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|