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Iranian Journal of Otorhinolaryngology، جلد ۳۶، شماره ۱، صفحات ۳۴۳-۳۴۸
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عنوان انگلیسی Preoperative Vitamin.D Status and Post-Total Thyroidectomy Hypocalcemia
چکیده انگلیسی مقاله Introduction: Hypocalcemia is a common complication of total thyroidectomy (TT). This study was designed to investigate the effect of preoperative vitamin.D (Vit.D) status on the occurrence of post-total thyroidectomy hypocalcemia.Materials and Methods: Patients who underwent TT without parathyroidectomy were divided into three groups based on their preoperative Serum Vit.D levels (<20 ng/ml, 20-30 ng/ml, and ≥30 ng/ml were considered deficient, insufficient, and normal Vit.D levels, respectively). Serum levels of calcium and phosphorus were measured before and 24 hours after surgery in all patients. The patients were examined for clinical symptoms and signs of hypocalcemia postoperatively. In cases with positive clinical symptoms and signs of hypocalcemia and/or calcium levels <8 mg/dl, PTH level was measured before starting calcium infusion, while serum calcium and phosphorus levels were also measured 24 hours later.Results:Among 100 patients enrolled in this study, 81% were females. The mean age was 36.60±8.32 years. Before surgery, the mean Vit.D level was 26.9±16.89 ng/ml, while 47% of cases had normal Vit.D level, 32% had insufficient vitamin levels, and 21% had Vit.D deficiency. Twenty-four hours after surgery, the calcium (P=0.356) and phosphorus (P=0.743) levels were not significantly different between the three Vit.D groups. A comparison of postoperative PTH levels between the three Vit.D groups showed no significant difference (P=0.596).Conclusions:Based on our findings, preoperative serum Vit.D levels did not affect postoperative serum calcium levels.
کلیدواژه‌های انگلیسی مقاله Hypocalcemia, Vitamin.D, Total thyroidectomy
نویسندگان مقاله | Parvin Layegh
Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.


| Zakie Sadat Sajjadi
Department of Otorhinolaryngology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.


| Leila V.Mostaan
Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.


| Masoud Mohebbi
Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.


| Mona Kabiri
Nanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.


| Mohammad ali Yaghoubi
Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
نشانی اینترنتی https://ijorl.mums.ac.ir/article_23661.html
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