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Journal of Dental Materials and Techniques، جلد ۱۲، شماره ۴، صفحات ۱۸۰-۱۸۵
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عنوان انگلیسی The efficacy of supragingival irrigation with chlorhexidine for plaque control in patients with hematologic malignancies: A randomized clinical trial
چکیده انگلیسی مقاله Objective: Oral and dental problems are important issues in patients suffering from hematologic malignancies. This study aimed to assess the efficacy of supragingival irrigation with chlorhexidine in improving the oral health status of patients with hematologic malignancies.Methods: This randomized, single-blind, controlled clinical trial, included 32 patients suffering from blood dyscrasia and hospitalized in Imam-Reza Hospital, Mashhad, Iran. Participants were randomly allocated to intervention and control groups. The control subjects received routine dental care by cleaning their teeth daily with sterilized gauze soaked in normal saline. For the intervention group, supra-gingival irrigation with chlorhexidine was performed in addition to routine dental care. The Debris Index Simplified (DI-S) part of the Oral hygiene index-simplified (OHI-S) index was recorded in all patients at baseline (T0), one (T1), two (T2), and three (T3) weeks later. The World Health Organization (WHO) scale was used to assess oral mucositis.Results: DI-S decreased significantly in the intervention group (P<0.001), and increased significantly in the control group (P=0.04) over the experiment. The study groups had comparable DI-S values at baseline (T0; P=0.48). However, DI-S scores were significantly lower in the experimental than in the control group at T1, T2, and T3 time points (P=0.002, P<0.001, and P<0.001, respectively). Oral mucositis was observed in only five patients in the control group.Conclusions: Supra-gingival irrigation with chlorhexidine can improve oral hygiene during chemotherapy and may be used by patients and oral care providers in hospital settings.
کلیدواژه‌های انگلیسی مقاله Chlorhexidine, Dental plaque, Gingivitis, Hematologic malignancies, irrigation, Oral hygiene
نویسندگان مقاله | Pegah Mosannen Mozafari
Oral & Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.


| Seyed MohammadReza Aboutorabzadeh
Private Practice, Mashhad, Iran.


| Mahdokht Rashed Mohassel
Department of Pediatric and Oral Medicine, School of Dentistry, North Khorasan University of Medical Sciences, Bojnurd, Iran


| Mohammad Mahdi Koshyar
Department of Hematology and Oncology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.


| Maryam Amirchaghmaghi
Oral & Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.


| Ershad Aghasizadeh
Department of Periodontology, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.


| Parisa Karoos
Private Practice, Mashhad, Iran.


| Amir Abbas Azarian
Department of Statistics, Mashhad University of Medical Sciences, Mashhad, Iran
نشانی اینترنتی https://jdmt.mums.ac.ir/article_23611.html
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