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International Journal of Engineering، جلد ۳۳، شماره ۹، صفحات ۱۶۹۶-۱۷۰۲
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Determination of Riboflavin by Nanocomposite Modified Carbon Paste Electrode in Biological Fluids Using Fast Fourier Transform Square Wave Voltammetry |
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| چکیده انگلیسی مقاله |
Herein, fast Fourier transformation square-wave voltammetry (FFT-SWV) as a novel electrochemical determination technique was used to investigate the electrochemical behavior and determination of Riboflavin at the surface of a nanocomposite modified carbon paste electrode. The carbon paste electrode was modified by nanocomposite containing Samarium oxide (Sm2O3)/reduced graphene oxide (RGO) (2:1) to improve detection sensitivity of Riboflavin under optimal experimental conditions. Furthermore, the signal-to-noise ratio was significantly increased by application of discrete fast Fourier transformation analysis, background subtraction and two-dimensional integration of the electrode response over the selected potential range and the time window. Obtained cyclic voltammograms demonstrated a diffusion-controlled reversible electron transfer reaction for Riboflavin in phosphate buffer solution (pH=7.2). The peak potential values were pH-dependent, involving the same numbers of protons and electrons. To obtain the maximum sensitivity, some effective parameters such as scan rate (10 mV/s), accumulation time (0.2 s) and potential (+400 mV), frequency (1420 Hz) and amplitude (20 mV) were optimized. As a result, determination of Riboflavin using FFT-SWV showed a linear range of response from 10 to 400 nM (R2=0.9993), with limit of detection of 0.86 nM. An acceptable recovery percent was also obtained for Riboflavin in human plasma samples as criteria of measurement applicability of the proposed modified electrode. |
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| کلیدواژه‌های انگلیسی مقاله |
fast Fourier transforms square wave voltammetry,Riboflavin,Reduced graphene Oxide,Samarium Oxide |
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| نویسندگان مقاله |
M. Asgharian Marzabad |
CEITEC—Central European Institute of Technology and Department of Chemistry, Faculty of Science, Masaryk University, Kamenice 5, Czechia
B. Jafari |
Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran
P. Norouzi |
Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran+Biosensor Research Center, Endocrinology & Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
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| نشانی اینترنتی |
https://www.ije.ir/article_108476_043589a3456c9f6555eb0ace4cdd069a.pdf |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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